Results 91 to 100 of about 10,045,411 (259)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Shipin gongye ke-jiFood is vital to the people, and safety comes first in food. Food safety is crucial to people's livelihood, economic development, and social stability. It represents people's aspiration for a better life and grabs great public attention. In recent years,
Chun YANG +3 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Green design of circuit breaker electrical life to improve resource utilization
Scientific ReportsA qualified circuit breaker possesses an inherent electrical life upon leaving the factory. During its operational lifespan, this electrical life gradually diminishes due to various factors, including electrical and mechanical wear.
Jungang Zhou, Zhaoxia Shang
doaj +1 more source
Multi-product strategies and relative preferences for quality [PDF]
In this paper we investigate whether a monopoly in a vertically differentiated market may have the incentive to adopt a multi-product strategy if the consumers are concerned by the other consumers' choices.
Hend GHAZZAI
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Influencing factors and migration rules of 14 kinds of heavy metals in tableware
Shipin yu jixieObjectiveThis study focus on exploring the factors affecting the migration of 14 heavy metal elements such as Ag, As and Pb in tableware and the migration patterns of each element.MethodsSilver tableware was chosen as an example, and the following ...
TANG Shali +4 more
doaj +1 more source
Product Quality, Informality, and Child Labour [PDF]
This paper studies the interactions between the structure of product demand, relative wages, and the allocation of economic activity across two sectors.
Eugenia Fotoniata, Thomas Moutos
core
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Shipin yu jixieObjectiveTo establish a method for simultaneous determination of chlorothalonil and its metabolite 4-hydroxychlorothalonil residues in animal-derived food by ultra-high performance liquid chromatography-tandem mass spectrometry.MethodsThe samples were ...
LIU Xiaofang +4 more
doaj +1 more source