Results 101 to 110 of about 10,045,411 (259)

PRODUCT QUALITY AND DISTRIBUTION CHANNELS [PDF]

open access: yes
We introduce strategic behaviour in assigning a certain distribution channel to a product of a particular quality. We propose a variety of models to analyze and study some of the determinants of the choice of distribution channels.
José J. Sempere Monerris   +2 more
core  

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Determination of tetraniliprole residues in animal derived foods by multi-plug filtration cleanup combined with HPLC-MS/MS

open access: yesShipin yu jixie
ObjectiveThis study aimed to develop a rapid and efficient method for quantifying tetraniliprole residues in animal-derived foods by combining multi-plug filtration cleanup (m-PFC) with high-performance liquid chromatography-mass spectrometry (HPLC-MS ...
YUAN Liejiang   +4 more
doaj   +1 more source

Mixed oligopoly, vertical product differentiation and fixed quality-dependent costs [PDF]

open access: yes
A private and a public firm face fixed quality-dependent costs of production and compete first in quality and then either in prices or in quantities. In the long run the public firm targets welfare maximization whereas the private firm maximizes profits.
Mario Pezzino, Stefan Lutz
core  

A QFD framework for quality, innovation and high-tech product development dynamics [PDF]

open access: yes, 2010
The customer mostly chooses a product on the base of its quality, which therefore arises as the main cause of its commercial success. In a nearly axiomatic drawing, it follows that the effect of innovation is the improvement of quality, which itself ...
Franceschini, Fiorenzo   +2 more
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Application of Magnetic Nanoseparation Technology in Rapid Detection of Foodborne Pathogens

open access: yesShipin gongye ke-ji
Foodborne pathogens are important factors that contribute to foodborne illnesses, posing significant threats to food safety and human health, and presenting a major challenge for global healthcare systems. Contaminated food matrices are complex and often
Shilong DU   +4 more
doaj   +1 more source

Does tougher import competition foster product quality upgrading ? [PDF]

open access: yes
Over the past two decades, globalization, and more specifically the increased exposure to competition from low-price producers in China and India, has created a new economic environment for other emerging economies.
Fernandes, Ana M., Paunov, Caroline
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Vertical Product Differentiation When Quality is Unobservable to Buyers [PDF]

open access: yes
We analyze vertical product differentiation in a model where a good’s quality is unobservable to buyers before purchase, a continuum of quality levels is technologically feasible, and minimum quality is supplied under competitive conditions.
Gerhard Orosel, Klaus G. Zauner
core  

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