Results 121 to 130 of about 4,754,544 (311)

Baseline Sensitivity and Resistance Analysis of Fusarium graminearum to Pydiflumetofen in Henan Province, China

Journal of Fungi
Fusarium head blight (FHB), caused by Fusarium graminearum, severely threatens wheat production in China’s Huang-Huai region. In order to clarify the resistance status of F. graminearum to pydiflumetofen in Henan Province, the mycelial growth rate method
Yun Wang, Dongmei Liu, Haiyan Yin, Cheng Cao, Yingni Cao, Dan Feng, Guanghua Zhao, Hongqi Wang, Jihong Liu   +8 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Quality aspects of processed organic baby food - Results of a case study from an expert consultation in the baby food industry in 10 European countries. [PDF]

, 2008
The processor survey shows the general principles and understanding of quality for the processing of organic food from the processors’ point of view.
Kretzschmar, Ursula, Seidel, Kathrin, Zanoli, Raffaele   +2 more
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Dietary intake and risk assessment of sweeteners in prepared beverages among adolescents in Hunan province, China

Shipin yu jixie
ObjectiveTo verify the content of sweeteners in ready-made beverages in Hunan province, China, and the potential health risks to adolescents.MethodsTotal 850 samples of prepared beverages were collected from beverage stores across Hunan province, and the
HUANG Yan, XU Wenyang, YU Lan, LI Zheng, JIN Huihua   +4 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Product variety, product quality, and evidence of Schumpeterian endogenous growth: a note [PDF]

Using US manufacturing industry data, this paper re-examines empirical evidence of first- and second-generation Schumpeterian models of endogenous growth focusing on innovation (patent) quality.
Francesco Venturini
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Credibility Assessment for Digital Twins in Vehicle-in-the-Loop Test Based on Information Entropy

Sensors
Digital twins in vehicle-in-the-loop (VIL) test has great practical significance for the functional development, testing and evaluation of intelligent vehicle.
Tianfang Gao, Liang Chen, Xinghui Zhang, Jinghua Guo, Dong Ni   +4 more
doaj   +1 more source