Results 111 to 120 of about 10,045,411 (259)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Fusarium head blight (FHB), caused by Fusarium graminearum, severely threatens wheat production in China’s Huang-Huai region. In order to clarify the resistance status of F. graminearum to pydiflumetofen in Henan Province, the mycelial growth rate method
Yun Wang +8 more
doaj +1 more source
Quality and Competition: An Empirical Analysis across Industries, March 2006 [PDF]
This paper empirically explores the link between quality and concentration in a cross-section of manufactured goods. Using concentration data and product quality indicators, an ordered probit estimation explores the impact of concentration on quality ...
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
The Quality Management of New Product Design and Development [PDF]
The quality management of a modern complex product from design to production is very complicated matter which involves the whole company as well as external bodies (customer and supplier etc).
Wang, H. M.
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Honey is recognized for its high nutritional and functional value, yet it remains vulnerable to contamination by antibiotic residues such as tetracycline when beekeeping practices are not properly managed.
Fuad Al Alfarisi +5 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
ObjectiveTo verify the content of sweeteners in ready-made beverages in Hunan province, China, and the potential health risks to adolescents.MethodsTotal 850 samples of prepared beverages were collected from beverage stores across Hunan province, and the
HUANG Yan +4 more
doaj +1 more source

