Results 151 to 160 of about 1,387,172 (310)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Product Quality

AbstractManufacturing engineering considers accuracy to be the degree to which parameters of a finished product conform to the dimensions, shape, and other characteristics specified in a technical drawing. A designer determines the level of manufacturing accuracy and surface roughness based on requirements to ensure the functional purpose of a product.
Vitalii Ivanov, Artem Evtuhov, Ivan Dehtiarov, Justyna Trojanowska   +3 more
openaire   +1 more source

Factors Impacting Meat Product Quality: From Farm to Table. [PDF]

Foods
Bezerra LR, Ribeiro CVDM.
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Quality products

, 2018
Coverage ...
openaire   +2 more sources

Effects of feeding strategies on culture performance and product quality in NISTCHO. [PDF]

NPJ Syst Biol Appl
Schäpertöns V, Hofer L, Berger T, Štor J, Marx N, Esser-Skala W, Rauter T, Hofreither D, Liesinger L, Filzmoser P, Birner-Gruenberger R, Huber CG, Borth N, Fortelny N.   +13 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

How does agricultural product quality and safety regulation drive agricultural economic growth: a quasi-natural experiment from China's agricultural product quality and safety county pilot policy. [PDF]

Sci Rep
Zhang L, Zhang H.
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Vertical Product Differentiation, Entry-Deterrence Strategies, and Entry Qualities [PDF]

We analyze the potential entry of a new product into a vertically differentiated market. Here the entry-deterrence strategies of the incumbent firm rely on ﾓlimit qualities.ﾔ The model assumes quality-dependent marginal production costs and considers
Moschini, GianCarlo, Noh, Yong-Hwan
core