Results 161 to 170 of about 4,754,544 (311)

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Do Consumers Trust the National Inspection Exemption Brands? Evidence from Infant Formula in China [PDF]

open access: yes
Consumers are often uncertain about product quality and have to rely on different information, either given or pursued, to assess quality. Developing countries may lack institutional and technical resources to rigorously monitor and enforce product ...
Jin, Yanhong H., Lin, Liguo, Yao, Lan
core   +1 more source

Phytochemicals in Ruminant Diets: Mechanistic Insights, Product Quality Enhancement, and Pathways to Sustainable Milk and Meat Production-Invited Review. [PDF]

open access: yesAnimals (Basel)
Priyashantha H   +6 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Product Quality in the Food Chain: Do Cooperatives Offer High Quality Products? [PDF]

open access: yes
Cooperatives and investor-owned firms are alternative forms of business organisation that coexist and compete in many markets. The theoretical literature has identified a number of comparative advantages and disadvantages of cooperatives.
Pennerstorfer, Dieter   +1 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

PENGARUH CITRA MEREK DAN KUALITAS PRODUK TERHADAP KEPUTUSAN PEMBELIAN SEPEDA MOTOR (Studi Pada Konsumen Honda Beat di Kecamatan Sukun, Kota Malang) [PDF]

open access: yes
The Influence of Brand Image on Purchase Decision, the Influence of Product Quality on Purchase Decision, and the Dominant Influence between Brand Image and Product Quality on Purchase Decision. This research was conducted in the Sukun District of Malang
ROSYIDI, MOCHAMMAD IMAM
core  

Enhancing 3D Printing Performance and Product Quality Through the Valorization of Food By-Products and Waste. [PDF]

open access: yesCompr Rev Food Sci Food Saf
Bareen MA   +6 more
europepmc   +1 more source

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