Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Product Quality, Product Price, and Share Dynamics in the German Compact Car Market [PDF]
The present paper examines one of the central elements of evolutionary thinking - competition formalized by the replicator dynamics mechanism. Using data on product characteristics of automobiles sold on the German domestic market over the period 2001 ...
Jens J. Krüger +2 more
core
Green agricultural product quality supervision based on prospect theory and evolutionary game theory for logistics enterprise live streaming. [PDF]
Sci RepHu Q, Guo E, Feng F, Zhao S.
europepmc +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Trade performances, product quality perceptions and the estimation of trade price-elasticities [PDF]
Traditional trade models ignoring the dimension of product quality generally lead to excessively low trade price elasticities. In this paper, we show that higher estimated trade price elasticities, more in conformity with theory, can be obtained by ...
Hélène Erkel-Rousse, Matthieu Crozet
core
Bee-Derived Products in Aquaculture Nutrition: A Comprehensive Review of Impacts on Fish Performance, Health, and Product Quality. [PDF]
Animals (Basel)Lo Presti V, Cavallaro M, Di Rosa AR.
europepmc +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Do Cooperatives Offer High Quality Products? [PDF]
The present paper investigates the free-riding problem in determining product quality within cooperatives in a vertically related market. Whereas the individual member has to bear all costs associated with higher quality, the benefits of delivering ...
Pennerstorfer, Dieter +1 more
core +1 more source
Near-Infrared Spectroscopy Combined with Chemometrics for Liquor Product Quality Assessment: A Review. [PDF]
FoodsQi W +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source