Results 191 to 200 of about 10,045,411 (259)

Metabolic and functional analysis including repetitive antigen stimulation provides a more accurate assessment for CAR-T cell product quality and long-term functionality. [PDF]

J Transl Med
Guijarro-Albaladejo B, Sierro-Martínez B, Carrasco-Brocal I, Hernández-Díaz P, de la Rosa-Garrido M, Muñoz-García R, Bejarano-García JA, Mañé-Pujol J, Alcalde-Mellado P, Rodríguez-Gil A, Escamilla-Gómez V, Lara-Chica M, Aguirre-Portolés C, Galán-Gómez V, Escribà-García L, Español-Rego M, Rodríguez-Lobato LG, Briones J, Fernández-de Larrea C, Pérez-Martínez A, Bella Á, Pérez-Simón JA, García-Guerrero E.   +22 more
europepmc   +1 more source

PRODUCT QUALITY MANAGEMENT MAY REPORT.

, 1986
PRODUCT QUALITY MANAGEMENT
core  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Impact of High-Shear Homogenization Pretreatment on Process Productivity, Economic Feasibility, and Product Quality During Long-Term Crossflow Microfiltration of Andean Blackberry Juice. [PDF]

Foods
Rodríguez P, Zuluaga J, González S, Escobar V, Cortés M, Vaillant F.   +5 more
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Phytochemicals in Ruminant Diets: Mechanistic Insights, Product Quality Enhancement, and Pathways to Sustainable Milk and Meat Production-Invited Review. [PDF]

Animals (Basel)
Priyashantha H, Jayathissa IS, Vidanarachchi JK, Jayarathna S, Mapiye C, Maggiolino A, Ponnampalam EN.   +6 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Decision theoretic fuzzy modelling for product quality and design evaluation of basketballs using deck of cards strategy. [PDF]

Sci Rep
Zhu A.
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Enhancing 3D Printing Performance and Product Quality Through the Valorization of Food By-Products and Waste. [PDF]

Compr Rev Food Sci Food Saf
Bareen MA, Antonio D, Corradini MG, Rossella C, Paolo D, Marta S, Carla S.   +6 more
europepmc   +1 more source