Results 91 to 100 of about 610,727 (313)

Hermite-Hadamard's Inequality and the p-HH-Norm on the Cartesian Product of Two Copies of a Normed Space

open access: yes, 2008
The Cartesian product of two copies of a normed space is naturally equipped with the well-known p-norm. In this paper, another notion of norm is introduced, and will be called the p-HH-norm. This norm is an extension of the generalised logarithmic mean
Dragomir, Sever S, Kikianty, Eder
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Navigating a Service Robot for Indoor Complex Environments

open access: yesApplied Sciences, 2019
This paper investigates the use of an autonomous service robot in an indoor complex environment, such as a hospital ward or a retirement home. This type of service robot not only needs to plan and find paths around obstacles, but must also interact with ...
Jong-Chih Chien   +2 more
doaj   +1 more source

FORECASTING METHOD FOR DISRUPTIVE SPACE TECHNOLOGIES

open access: yes, 2010
This paper documents a research initiative performed on Disruptive Space Technologies (DST) in the European space sector and elaborates on a method of forecasting them. The research was performed at the DLR in Bremen in co-operation with the University
van der Veen, Egbert Jan
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Decoded fingerprints of hyperresponsive, expanding product space: polyether cascade cyclizations as tools to elucidate supramolecular catalysis. [PDF]

open access: yesChem Sci, 2022
Chen H   +8 more
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

"Product Complexity and Economic Development" [PDF]

open access: yes
We rank 5,107 products and 124 countries according to the Hidalgo and Hausmann (2009) measures of complexity. We find that: (1) the most complex products are in machinery, chemicals, and metals, while the least complex products are raw materials and ...
Marife Bacate   +3 more
core  

Product relationships management enabler for concurrent engineering and product lifecycle management

open access: yes, 2013
The current competitive industrial context requires more flexible, intelligent and compact product lifecycles, especially in the product development process where several lifecycle issues have to be considered, so as to deliver lifecycle oriented ...
Kiritsis, Dimitris   +6 more
core   +1 more source

Probability theory and causation. A branching space-times analysis [PDF]

open access: yes, 2004
We provide a formally rigorous framework for integrating singular causation, as understood by Nuel Belnap's theory of causae causantes, and objective single case probabilities.
Thomas Müller, Muller, Thomas
core   +1 more source

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