Results 71 to 80 of about 739,909 (264)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Effects of turmeric addition to broiler starter on growth performance, nutrient digestibility, and production economics

Животновъдни науки
The research aimed to assess how feeding broiler chicks’ diets supplemented with turmeric meal affected their growth performance, nutrient digestibility, and production economics.
Taiwo Ayobami Sunmola, Comfort Dooshima Tuleun   +1 more
doaj   +1 more source

Balancing WAAM Production Costs and Wall Surface Quality through Parameter Selection: A Case Study of an Al-Mg5 Alloy Multilayer-Non-Oscillated Single Pass Wall

Journal of Manufacturing and Materials Processing, 2019
The purpose of the study was to propose a strategy to assess the potential reduction of the production cost during wire+arc additive manufacturing (WAAM) based on the combination of wire feed speed (related to deposition rate) and travel speed (related ...
Yuri Yehorov, Leandro João da Silva, Américo Scotti   +2 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Reduced density is an environmental friendly and cost effective solution to increase resilence to drought in vineyards in a contexte of climate change

OENO One, 2019
Aims: Climate change imposes increasingly warm and dry conditions in most winegrowing regions. Mediterranean vineyards are particularly vulnerable and have registered, in most situations, declining yields over the past years.
Cornelis van Leeuwen, Philippe Pieri, Mark Gowdy, Nathalie Ollat, Jean-Philippe Roby   +4 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Determinação de custos como ação de competitividade: estudo de um caso na avicultura de corte Management of costs as action of agricultural company competitiveness: a study case

Ciência e Agrotecnologia, 2008
Trata-se no presente trabalho de um estudo de caso, tendo sido desenvolvido com o objetivo de mostrar a importância do gerenciamento de custos como ação de competitividade da empresa agropecuária.
Francisval de Melo Carvalho, Marco Antônio Fiúza, Marcos Aurélio Lopes   +2 more
doaj   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Assessing the operational efficiency of the agricultural machinery fleet at a modern agro-industrial enterprise

Управление
In the cost structure of agricultural production, fuel and lubricant costs (hereinafter referred to as FLC) account for a significant share and are subject to high price volatility, which creates substantial economic risks.
M. Yu. Karelina, M. S. Chekusov, D. V. Serdechnyi, V. V. Filatov, V. D. Kutkov, N. S. Akinshin   +5 more
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source