Results 241 to 250 of about 8,484,068 (292)

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

A Paired Ileum-Caecum Study of the Goose Gut Microbiome in Response to Fattening Protocol and Postbiotic Supplementation. [PDF]

Animals (Basel)
Baka E, Kovács-Weber M, Ábrahám R, Pap TI, Táncsics A, Szabó G, Heincinger M, Szabó S, Dolányi Á, Berta AI, Kovács B, Szabó RT.   +11 more
europepmc   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

The microbiome bone axis in osteomyelitis: integrating evidence from bone oral and gut microbiota. [PDF]

Microbiome Res Rep
Kunasol C, Piyaphattachai C, Saengsin J, Chattipakorn N, Chattipakorn SC.   +4 more
europepmc   +1 more source

Inter-breed diversity and temporal dynamics of the fecal microbiota in two local chicken breeds from karst regions in China. [PDF]

Poult Sci
Wang Z, Xiao Q, Wang M, Yue Y, Du S, Zhang F, Cui X.   +6 more
europepmc   +1 more source

Dominance of ascomycota and ubiquity of <i>Trichoderma</i> in <i>Argemone mexicana</i> microbiomes across Assam, India. [PDF]

Front Fungal Biol
Singh P, Sharma A, Kumar Sarmah B, Arivaradarajan P, Nath T, Nandi SP.   +5 more
europepmc   +1 more source