Results 51 to 60 of about 12,429,939 (247)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Optimisation estimation of uncertainty integrated with production information based on Bayesian fusion method

open access: yesThe Journal of Engineering, 2019
The new generation Geometrical Product Specifications require consideration of the effects of measurement uncertainty in the product inspection. This study estimated the measurement results and the uncertainty by integrating the statistical production ...
Yinbao Cheng   +5 more
doaj   +1 more source

Ethical Applications of Big Data-Driven AI on Social Systems: Literature Analysis and Example Deployment Use Case

open access: yesInformation, 2020
The use of technological solutions to address the production of goods and offering of services is ubiquitous. Health and social issues, however, have only slowly been permeated by technological solutions.
Paulo Garcia   +3 more
doaj   +1 more source

Parallel Cross-section Recognition of Geometrical Features for Selected Machine Parts

open access: yesJournal of Machine Engineering, 2021
Increase of automation and autonomy of production is the latest trend incorporated into Industry 4.0 objectives. Production autonomy is very desirable in the field of damaged parts replacement.
Marcin Gołaszewski   +2 more
doaj   +1 more source

The Role of Cloud Computing in Industrial Production Engineering

open access: yesAmerican Journal Of Industrial And Production Engineering, 2022
Cloud computing has transformed industrial production engineering by enhancing flexibility, efficiency, and data-driven decision-making. This paper explores the integration of cloud technologies in manufacturing and production processes, highlighting their impact on productivity, resource management, and innovation.
openaire   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

A Comparison of Simulation’s Results with Experiment on Water Mitigation of an Explosion

open access: yesShock and Vibration, 1999
This paper presents a comparison of simulation’s results with the experimental data from a series of small-scale tests conducted by Joachim and Lunderman of the United States Army Engineer Waterways Experiment Station.
W.K Chong   +4 more
doaj   +1 more source

Design of tool-state monitoring system based on current method

open access: yesThe Journal of Engineering, 2019
Tool failure is one of the main causes of failure in CNC machine tool machining. The real-time online monitoring technology of CNC machine tool is studied, which is helpful to improve the efficiency of failure-free operation of CNC machine tool and ...
Weiwei Sun   +3 more
doaj   +1 more source

Plant Factory: A New Playground of Industrial Communication and Computing

open access: yesSensors, 2021
Plant Factory is a newly emerging industry aiming at transforming crop production to an unprecedented model by leveraging industrial automation and informatics.
Yu Liu   +5 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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