Results 71 to 80 of about 1,962,028 (312)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

21st International Symposium on Production Research (ISPR) - Digitizing Production System

, 2022
Part of the book series: Lecture Notes in Mechanical Engineering ((LNME)).In this study, the transportation problem is considered in order to minimize the total traveling distance between the nodes.
KULLAB, HUTHAYFAH, ABOUSALEH, RAED, ÜLKÜ, İLAYDA, ALMSADI, ALI, AL MULQI, TALHA   +4 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Some Empirical Evidence on the Production Level and Production Cost Smoothing Models of Inventory Investment [PDF]

The production smoothing model of inventories has long been the basic paradigm within which empirical research on inventories has been conducted The basic hypothesis embedded In this model IS that inventories of finished goods serve primarily to smooth ...
Martin S. Eichenbaum
core  

Enhanced production surveillance using probabilistic dynamic models

International Journal of Prognostics and Health Management, 2018
Production surveillance is the task of monitoring oil and gas production from every well in a hydrocarbon field. A key opportunity in this domain is to improve the accuracy of flow measurements per phase (oil, water, gas) from a multi-phase flow.
Ashutosh Tewari, Stijn de Waele, Niranjan Subrahmanya   +2 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Physical robustness of canopy temperature models for crop heat stress simulation across environments and production conditions

, 2017
Despite widespread application in studying climate change impacts, most crop models ignore complex interactions among air temperature, crop and soil water status, CO2 concentration and atmospheric conditions that influence crop canopy temperature.
Ababaei, B., White, J. W., Ewert, F., Reynolds, M. P., Wall, G. W., Doltra, J., Webber, H., Hatfield, J., Leavitt, S. W., Kersebaum, K.-C., Bindi, M, Stratonovitch, P., Semenov, M. A., Olesen, J. E., Asseng, S., Ferrise, R., Kimball, B. A., Rezaei, E. E., Kage, Henning, Pinter, P. J., LaMorte, R. L., Hunsaker, D. J., Martre, P., Luig, A., Kassie, B.T., Ratjen, A. M.   +25 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Estimating State-Contingent Production Frontiers [PDF]

Chambers and Quiggin (2000) advocate the use of state-contingent production technologies to represent risky production and establish important theoretical results concerning producer behaviour under uncertainty.
C.J. O'Donnell, W.E. Griffiths
core   +2 more sources

Psycholinguistic models of oral verbal language production

Gragoatá, 2018
Psycholinguistic models of verbal language production face at the difficulty of formalizing the mental representations that govern pragmatic intentions for producing an oral text, as well as that of the essential concepts, both with the function of ...
Leonor Scliar-Cabral
doaj   +1 more source