Results 111 to 120 of about 1,001,507 (243)

Effects of Blautia coccoides CML164 on production performance and meat quality in broiler chickens. [PDF]

Poult Sci
Gao Z, Li Z, Deng S, Liang S, Nie M, Liu D.   +5 more
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Does age in months influence Chinese Holstein dairy cow production performance after controlling for days in milk? [PDF]

Front Vet Sci
Zhang L, Luo CL, Mu Q, Liu JC, Li CF, Ma YB, Su Q, Zhang JP, Li JT, Zhang SY, Chai JM, Zhao YL.   +11 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Effects of Dietary Black Soldier Fly Larvae on Production Performance and Cecal Microbiota of Yunshang Countryside Chickens. [PDF]

Vet Sci
Sun D, Fu Y, Wang W, Zhang B, Yang R, Duan H, Li X, Lan Y, Ren W, Zhang J, Zhao Z.   +10 more
europepmc   +1 more source

Production assurance performance

, 2007
The concept of Production Assurance increasingly plays an important role to support the decision-making process for the managers and engineers dealing with challenges to meet the varying demand of customers as well as production control. The Production Assurance concept incorporates several other concepts such as availability, reliability ...
Kumar, Uday, Barabady, Javad
openaire   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Dietary starch levels modulate production performance and whole-body nutrient metabolism in dairy cows. [PDF]

JDS Commun
Arshad U, Huser M, Barrientos-Blanco MA, Islam MZ, Ma X, Peng R, Wang K, Niu M.   +7 more
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

The optimal dietary crude protein level improves goat production performance by enhancing the body's antioxidant function and energy metabolism. [PDF]

Front Microbiol
Wang C, Zhang C, Shah AM, Wang Z, Qiu S, Xu Z, Xue B, Wang L, Hu R, Zou H, Jiang Y, Xiao J, Peng Q.   +12 more
europepmc   +1 more source