Results 31 to 40 of about 1,001,507 (243)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Dregs of Cardamine hupingshanensis as a feed additive to improve the egg quality

Frontiers in Nutrition, 2022
Natural plant herbs have many active compounds to prevent poultry diseases and improve poultry products. However, most herbs are supplied for human medicine. Thus, for economic and sustainable development purposes, the dregs of Cardamine hupingshanensis (
Feike Yu, Xiaohan Yu, Rongchen Liu, Dawei Guo, Qian Deng, Bingbing Liang, Xiaoye Liu, Xiaoye Liu, Hong Dong, Hong Dong   +9 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Rumen microbial dysbiosis is associated with productive lifespan decline in dairy cows via metabolic-inflammatory crosstalk

Microbiome
Background Gut microbiota has been established as a critical regulator of human longevity, but the mechanistic role of rumen microbiota in dairy cow productive lifespan remains unexplored.
Panping Yang, Lei Yan, Zhuoxuan Wu, Yujia Li, Yuefei Yan, Feng Zhou, Shuhua Gu, Changlei Liu, Xiaoli Ren, Zhiyang Zhang, Shanshan Gao, Chaoying Huang, Yaqin Wang, Jingwen Dai, Shuai Qin, Yang Zhang, Huixia Li, Zhen Zhang   +17 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Production performance, egg quality, and uterine gene expression for layers as affected by N-Carbamylglutamate supplementation

Frontiers in Veterinary Science, 2023
IntroductionSupplementation of exogenous additives is a strategy to improve laying performance of layers by regulating uterine function. N-Carbamylglutamate (NCG) as an activator for endogenous arginine synthesis has the potential to regulate the laying ...
Wei Ma, Yi Lu, Chunqiang Wang
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The Impact of Distillers Dried Yeast on the Production Performance and Fecal Microbiome of Broiler Chickens

Agriculture, 2023
The aim of this research was to assess the influence of partially substituting post-extraction soybean meal with distillers dried yeast on the efficiency of broiler chicken fattening and the intestinal microflora.I Inactive distillers dried yeast ...
Artur Rybarczyk, Elżbieta Bogusławska-Wąs, Kamil Sierżant, Izabella Tobolska   +3 more
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Effects of Clostridium butyricum on Production Performance and Bone Development of Laying Hens

Veterinary Sciences
Probiotics are safe, inexpensive, and effective feed additives, and Clostridium butyricum (CB) has been reported to regulate bone health in addition to having conventional probiotic effects.
Jiaqi Huang, Lulu Cui, Hai Lin, Mengze Song, Shuhong Sun   +4 more
doaj   +1 more source