Results 61 to 70 of about 1,001,507 (243)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Effects of dietary mulberry leaves on growth, production performance, gut microbiota, and immunological parameters in poultry and livestock: a systematic review and meta-analysis [PDF]

Animal Bioscience
Objective This study aimed to assess the effects of dietary mulberry leaves on the growth, production performance, gut microbiota, and immunological parameters of poultry and livestock. Methods The PubMed, Embase, and Scopus databases were systematically
Bing Geng, Jinbo Gao, Hongbing Cheng, Guang Guo, Zhaohong Wang   +4 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Desempenho comparativo de três linhagens de tilápia do Nilo Oreochromis niloticus em diferentes densidades de estocagem = Comparative performance of three Nile Tilapia Oreochromis niloticus strains in different stocking densities

Acta Scientiarum: Animal Sciences, 2009
O presente trabalho objetivou avaliar o desempenho produtivo de trêslinhagens de tilápia do Nilo (O. niloticus) na fase inicial e de crescimento, em diferentes densidades de estocagem. As linhagens estudadas foram Bouaké, Chitralada e GIFT.
Vanice Marli Fülber, Lauro Daniel Vargas Mendez, Graciela Lucca Braccini, Nelson Maurício Lopera Barrero, Melanye Digmeyer, Ricardo Pereira Ribeiro   +5 more
doaj  

Comparative Study on Production Performance of Different Oat (Avena sativa) Varieties and Soil Physicochemical Properties in Qaidam Basin

Plants
Oats (Avena sativa L.) are forage grasses moderately tolerant to saline-alkali soil and are widely used for the improvement and utilization of saline-alkali land. Using the oat varieties collected from the Qaidam Basin as experimental materials, based on
Wenqi Wu, Ronglin Ge, Jie Wang, Xiaoli Wei, Yuanyuan Zhao, Xiaojian Pu, Chengti Xu   +6 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

The Effect of Feeding Native Grass, Jackfruit Leaves and Leguminosa on Daily Weight Increase and Body Sizes of Goats

Jurnal Nutrisi Ternak Tropis
The use of foliage and legumes in goat diet is essential to serve protein sources for maintenance and productivity. This study aimed to evaluate the effect of providing native grass, jackfruit leaves (Artocarpus heterophyllus), and different legumes such
Muhammad Ade Salim, Dwi Hariyono
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

A Semi-Analytical Method for Simulating Two-Phase Flow Performance of Horizontal Volatile Oil Wells in Fractured Carbonate Reservoirs

Energies, 2018
Two-phase flow behavior in fractured carbonate reservoirs was investigated due to the importance for geothermal and petroleum resource recovery, such as in this study the phase change of volatile oil.
Suran Wang, Linsong Cheng, Yongchao Xue, Shijun Huang, Yonghui Wu, Pin Jia, Zheng Sun   +6 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source