Results 91 to 100 of about 4,393,221 (308)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Impact of a homestead food production program on women's empowerment: Pro-WEAI results from the FAARM trial in Bangladesh. [PDF]

World Dev, 2022
Waid JL, Wendt AS, Sinharoy SS, Kader A, Gabrysch S.   +4 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

YOLOv8m for Automated Pepper Variety Identification: Improving Accuracy with Data Augmentation

Applied Sciences
This research addresses the critical need for an efficient and precise identification of Capsicum spp. fruit varieties within the post-harvest contexts to enhance quality control and ensure consumer satisfaction.
Madalena de Oliveira Barbosa, Fernanda Pereira Leite Aguiar, Suely dos Santos Sousa, Luana dos Santos Cordeiro, Irenilza de Alencar Nääs, Marcelo Tsuguio Okano   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Carbon Footprint of Electricity Generation in Brazil: An Analysis of the 2016–2026 Period

Energies, 2018
The present paper aims to evaluate the past and future environmental performance of the electricity generation in Brazil in terms of Global Warming Potential (GWP) and Global Temperature Potential (GTP).
Murillo Vetroni Barros, Cassiano Moro Piekarski, Antonio Carlos de Francisco   +2 more
doaj   +1 more source

Assessing Participation in the Milk Income Loss Contract Program and its Impact on Milk Production [PDF]

The MILC program, a counter-cyclical income support program, was designed to provide price support to dairy farmers. Since the inception of the MILC program it has been argued that the program is inefficient and rewards inefficiency by keeping high cost,
D'Antoni, Jeremy M., Mishra, Ashok K.
core   +1 more source

The Determining Factors of Entrepreneurial Activity in Broiler Farms [PDF]

, 2013
Indonesia still requires approximately 4 million entrepreneurs to become a developed country. This research aimed at identifying and analyzing the factors forming the broiler farm entrepreneurial activities that contribute on generating new entrepreneurs
Burhanuddin, B. (Burhanuddin), Harianto, H. (Harianto), Nurmalina, R. (R), Pambudy, R. (R)   +3 more
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Productive Programming of GPU Clusters with OmpSs

2012 IEEE 26th International Parallel and Distributed Processing Symposium, 2012
Clusters of GPUs are emerging as a new computational scenario. Programming them requires the use of hybrid models that increase the complexity of the applications, reducing the productivity of programmers. We present the implementation of OmpSs for clusters of GPUs, which supports asynchrony and heterogeneity for task parallelism.
Javier Bueno, Judit Planas, Alejandro Duran, Rosa M. Badia, Xavier Martorell, Eduard Ayguadé, Jesús Labarta   +6 more
openaire   +2 more sources