Results 131 to 140 of about 1,415,684 (317)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

MODELING FARM AND OFF-FARM ECONOMIC LINKAGES TO ANALYZE THE IMPACTS OF AN AREA-WIDE INSECT MANAGEMENT PROGRAM ON A REGIONAL ECONOMY

This study evaluated the impacts of the boll weevil eradication program at the farm level and on the west Tennessee region. Budgets, an acreage response model, and an input-output model were used to evaluate direct and indirect program impacts.
English, Burton C., Larson, James A., Suarez, Otto P.   +2 more
core  

Beef

, 2013
Highlights of the beef production systems research program, focusing on recent research. More than 25 expert researchers conduct production systems research related to beef cattle.
Ball, Brita
core  

Monitoring Brazilian Food Security Based on Emergy Concepts: A Proposed Approach

Resources
This study enhances the discussion on food security by examining trade equity between food consumers and the supply chain from an emergy perspective.
Rafael Araujo Nacimento, Mario Duarte Canever, Luiz Carlos Terra dos Santos, Cecília Almeida, Feni Agostinho, Biagio Fernando Giannetti   +5 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Dairy

, 2013
Highlights of the dairy production systems research program, focusing on recent research. More than 60 expert researchers conduct production systems research relating to dairy cattle. State-of-the-art facilities and herds at two research stations provide
Ball, Brita
core  

Tagungsband zur 2. Tierwohltagung des Promotionsprogramms „Animal Welfare in Intensive Livestock Production Systems“

, 2019
Am 17. & 18.10.2019 fand in der alten Mensa am Wilhelmsplatz in Göttingen die 2. Tierwohltagung statt, organisiert von den DoktorandInnen des Promotionsprogramms „Animal Welfare in Intensive Livestock Production Sytems“.
Promotionsprogramm „Animal Welfare in Intensive Livestock Production Systems“
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

AUTONOMOUS CT REPLACEMENT METHOD FOR THE SKULL PROSTHESIS MODELLING

Facta Universitatis. Series: Mechanical Engineering, 2015
The geometric modeling of prosthesis is a complex task from medical and engineering viewpoint. A method based on CT replacement is proposed in order to circumvent the related problems with the missing information to modeling.
Marcelo Rudek, Yohan Boneski Gumiel, Osiris Canciglieri Jr   +2 more
doaj  

Improvement in stands pricing and candidate companies allocation at agricultural exposition

Journal of the Saudi Society of Agricultural Sciences
Agricultural expositions are events aimed at product sales, training, technology dissemination, and integration between the agricultural sector and urban residents.
Ronier Gutierrez, Alvaro Neuenfeldt Júnior, Matheus Francescatto, Milton Mandlhate, Sabine De Paris   +4 more
doaj   +1 more source