Results 41 to 50 of about 4,154,339 (340)
Implementing R and D policies : an analysis of Spain's pharmaceutical research program [PDF]
, 2003 Using detailed firm-level data, we analyze Spain's Pharmaceutical Research Program, and find differences between the ex ante announced evaluation criteria and their ex post implementation.
Desmet, Klaus +3 more
core +1 more source
Patch Specifications via Product Programs
2023 IEEE/ACM 11th International Conference on Formal Methods in Software Engineering (FormaliSE), 2023 Code patches are the basic blocks of software evolution and several testing and analysis techniques have been proposed to validate them. However, due to lack of specifications, most of these techniques focus on generic errors, such as crashes.
Cadar, Cristian +2 more
openaire +2 more sources
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
From the Feds: Research, programs, and products [PDF]
Journal of Emergency Nursing, 2001 Health consequences among first responders after events associated with illicit methamphetamine laboratories: Methamphetamine, a central nervous system stimulant, is manufactured in illicit laboratories with use of over-thecounter ingredients. Many of these substances are hazardous and, when released from illicit laboratories, can place first ...
openaire +3 more sources
A Productivity Checker for Logic Programming [PDF]
, 2017 Automated analysis of recursive derivations in logic programming is known to be a hard problem. Both termination and non-termination are undecidable problems in Turing-complete languages. However, some declarative languages offer a practical work-around for this problem, by making a clear distinction between whether a program is meant to be understood ...
Ekaterina Komendantskaya +2 more
openaire +3 more sources
FEBS Letters, EarlyView.Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke +2 more
wiley +1 more source
Coal Combustion Products Extension Program [PDF]
, 2003 The primary objective of the CCP Extension Program is to promote the responsible uses of Ohio CCPs that are technically sound, environmentally safe, and commercially competitive. A secondary objective is to assist other CCP generating states (particularly neighboring states) in establishing CCP use programs within their states.
Butalia, T. S., Wolfe, W. E.
openaire +16 more sources
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source