Results 141 to 150 of about 13,376,299 (356)

Wage Setting and Passthrough: The Role of Market Power, Production Technology and Adjustment Costs

, 2023
Mons Chan, Elena Mattana, Sergio Salgado, Ming Xu   +3 more
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Rethinking production technology for meat packers. [PDF]

Anim Front, 2022
europepmc   +1 more source

Emergency medical resource allocation among hospitals with non-regressive production technology: A DEA-based approach. [PDF]

Comput Ind Eng, 2022
Chu J, Li X, Yuan Z.
europepmc   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Impact of "Three Red Lines" Water Policy (2011) on Water Usage Efficiency, Production Technology Heterogeneity, and Determinant of Water Productivity Change in China. [PDF]

Int J Environ Res Public Health, 2022
Shah WUH, Lu Y, Hao G, Yan H, Yasmeen R.
europepmc   +1 more source

Development of production technology of nanostructure monodisperse powder of different substances [PDF]

, 2010
Omar Khazamov, Magomed Ramadanov
openalex   +1 more source

Application of Novel Functional Materials and Evolving Technologies for Production and Storage of Renewable Energy

, 2022
Kamal Nain Chopra, Shivani Agarwal
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Hydrogen Production Technology Promotes the Analysis and Prospect of the Hydrogen Fuel Cell Vehicles Development under the Background of Carbon Peak and Carbon Neutrality in China. [PDF]

ACS Omega, 2022
Jiang J, Xie K, Liu Y, Sun H, Yang W, Yang H.   +5 more
europepmc   +1 more source