A Comparison of Frailty Indices in Predicting Postoperative Outcomes After Endoscopic Sinus Surgery
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Objective To compare the discriminatory performance of the Risk Analysis Index (RAI) and modified Frailty Index‐5 (mFI‐5) in predicting postoperative outcomes following endoscopic sinus surgery (ESS). Study Design Retrospective cohort study. Methods Adult ESS patients were identified from the ACS‐NSQIP database (2005–2020).
Akshay Warrier +6 more
wiley +1 more source
Porous Organic Cages for CO2 Capture and Confined Reduction
Angewandte Chemie, EarlyView.Porous organic cages (POCs) enable the coupling of CO2 capture and conversion through the interplay of molecular structure and solid‐state organization. Beyond intrinsic cavities, packing‐dependent pore accessibility and mass transport govern local CO2 concentration and catalytic performance, linking adsorption to reactivity in integrated capture ...
Valeria Amendola, Sonia La Cognata
wiley +2 more sources
Research progress on biomarkers of traumatic brain injury
Animal Models and Experimental Medicine, EarlyView.Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen +8 more
wiley +1 more source
Unlocking a Nitrosuccinate Lyase for Decarboxylative Enzymatic Hydronitration
Angewandte Chemie, EarlyView.The nitrosuccinate lyase CreD catalyzes C–NO2 bond formation using nitrite in water and shows synthetic practicality with high turnover numbers up to 102,000. A combination of protein engineering and computational methods helped to reveal the mechanistic principles that underpin this unique enzymatic activity.
Matteo Aleotti +9 more
wiley +2 more sources
Effects of the AMPPS One-on-One Mathematics Intervention on Students' Complex Computation, Word-Problem Solving, and Math Self-Concept. [PDF]
Behav Sci (Basel)Newson NK +4 more
europepmc +1 more source
Light‐Activated Isolation of High‐Quality Mitochondria for Therapeutic Transplantation
Angewandte Chemie, EarlyView.The Light‐Activated Mitochondrial Isolation (LAMI) platform enables the selective and non‐destructive isolation of high‐purity, metabolically active mitochondria. By integrating modular, ligand‐programmable magnetic probes with photo‐cleavable release, LAMI overcomes long‐standing limitations of conventional isolation methods and provides a robust ...
Hui Liu +12 more
wiley +2 more sources
Multicomponent Stapling of Glucagon‐Like Peptide‐1 Enables Receptor‐Guided PROTAC Delivery
Angewandte Chemie, EarlyView.We report a stapled glucagon‐like peptide‐1 (GLP‐1) analogue created via multicomponent tryptophan‐mediated Petasis reaction (TMPR). This strategy yields a stabilised peptide with superior helicity and improved potency. Conjugation to a bromodomain‐containing protein 4 (BRD4) degrader creates the first GLP‐1‐guided targeted protein degrader (PROTAC ...
Jan L. Venne +5 more
wiley +2 more sources
Ethnicity, gender, and social class in Honduras: an analysis using the permanent household survey. [PDF]
Front SociolNey Simons S +6 more
europepmc +1 more source
Supervising Resident AI Use Without Losing the Learning. [PDF]
J Grad Med EducPreiksaitis C.
europepmc +1 more source