Results 91 to 100 of about 1,776,568 (282)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Productive Remembering of Childhood: Child–Adult Memory-Work with the School Literary Canon
Humanities, 2019 This essay, co-written by adult and child researchers, marks an important shift in the field of children’s literature studies because it promotes an academic practice in which children are actively involved in decision-making.
Justyna Deszcz-Tryhubczak +9 more
doaj +1 more source
The Utilization of U.S. male labor, 1975-1992: Estimates of foregone work hours [PDF]
The percentage of working-age men in the United States who were fully active in the labor market decreased over the 1975-1992 period ("fully active" means working 2080 hours in a year).
L. Buron, O. O'Donnell, R. Haveman
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Social Interaction, Co-Worker Altruism, and Incentives [PDF]
Social interaction with colleagues is an important job attribute for many workers. To attract and retain workers, managers therefore need to think about how to create and preserve high-quality co-worker relationships.
Dur, Robert, Sol, Joeri
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Productive and Decent Work Employment Opportunities: Reflections of Sustainable Development Goal 8
Space and Culture, IndiaThis study measures the impact of seven indicators of Sustainable Development Goals (SDGs) on Goal 8, which is about productive and decent work and employment opportunities in India.
Deepika Chahal, Anju Rani
doaj +1 more source
Studies in Business and Economics, 2019 For decades, the concept of sustainability has been recognized as the basis for survival and further development of humanity. As the result of joint efforts, The 2030 Agenda for Sustainable Development was adopted in 2015 by United Nations member states,
Milica Đokić, Milica Jovanović
doaj +1 more source
Economic Freedom and the Advantages of Backwardness [PDF]
, 2007 According to econometric studies, economic freedom and its improvement increase growth rates. But their effects are dominated by the effects of the level of economic development and human capital.
Erich Weede
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source