Results 111 to 120 of about 1,776,568 (282)
Tips on Working From Home When You are on the Autism Spectrum [PDF]
, 2020 In the COVID19 world, we have additional need and expectation to be able to work remotely. For many on the Autism Spectrum (AS) who have been adjusting to work environments this change can be a big disruption.
DXC Technology
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Participation of Older Europeans in Volunteer Work [PDF]
Today’s discussion about the growing ‘burden of ageing’ must not neglect the substantial productive potential of the elderly population. Using micro-data from the new ‘Survey of Health, Ageing and Retirement in Europe’ (SHARE), we explore cross-national ...
Karsten Hank, Marcel Erlinghagen
core
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Frontiers in PsychologyThis research investigates the interactive effects of happiness at work and interest taking on work engagement and extra-productive behaviors across experienced employees and newcomers.ObjectiveThe article investigates how happiness at work can serve as ...
Patrik Fröhlich +2 more
doaj +1 more source
Productive government spending and private consumption: a pessimistic view [PDF]
This paper analyses the consequences of productive government spending on private consumption. In a related work, Linnemann and Schabert (2006) found that a moderate output elasticity of government expenditures is sufficient to generate a positive ...
Juha Tervala
core
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
US and UK Routes to Employment: Strategies to Improve Integrated Service Delivery to People with Disabilities [PDF]
In this report, the authors examine the experience of the United States and United Kingdom in developing effective strategies for providing integrated service delivery.
Boeltzig, H. +4 more
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source