Results 51 to 60 of about 1,978 (176)

Anxiety behavior in adult Zebrafish modulated by the alkaloid fraction of Cissampelos sympodialis Eichl. roots

Phytomedicine Plus
Cissampelos sympodialis (Menispermaceae), a species endemic to Brazil, it is used in folk medicine to treat inflammation and respiratory disorders. These activities are probably associated with the presence of alkaloids in the plant.
Johnatan Wellisson da Silva Mendes, Joice Barbosa do Nascimento, José Jonas Ferreira Viturino, Lariza Leisla Leandro Nascimento, Débora Odília Duarte Leite, Natália Kelly Gomes de Carvalho, Hélcio Silva dos Santos, Emmanuel Silva Marinho, Márcia Machado Marinho, Jane Eire Silva Alencar de Menezes, José Galberto Martins da Costa   +10 more
doaj   +1 more source

Produtos naturais com potencial leishmanicida

Revista de Ciências Farmacêuticas Básica e Aplicada, 2008
A leishmaniose é uma parasitose causada por protozoários do gênero Leishmania. É uma doença endêmica que abrange mais de 80 países, incluindo alguns do continente europeu e, principalmente, países sub-desenvolvidos ou em desenvolvimento. Nesta revisão discorre-se sobre as opções terapêuticas tradicionais e atuais, cuja atividade leishmanicida pode ...
E.S. Gil, J.R. Paula, F.R.F. Nascimento, J.C.B. Bezerra   +3 more
openaire   +2 more sources

Comprehensive Molecular Modeling Analysis of Betulin, a Triterpene Isolated from Miconia burchellii (Melastomataceae) Native to the Brazilian Cerrado

ChemistrySelect, Volume 10, Issue 40, October 27, 2025.
Betulin, isolated from the Brazilian Cerrado plant Miconia burchellii, was comprehensively characterized using X‐ray diffraction, DFT, and molecular modeling. Solid‐state analysis revealed stabilizing O···H and H···H contacts, while DFT calculations (HOMO–LUMO gap: 9.38 eV) indicated moderate stability.
Marianna C. Silva, Anderson J.L. Catão, Leonardo L. Borges, Antônio S.N Aguiar, Gracielle O.S. Cunha, Dayane C.A. Lima, Antônio C.S. Menezes, Alejandro P. Ayala, Hamilton B. Napolitano   +8 more
wiley   +1 more source

HSCCC Straightforward Fast Preparative Method for Isolation of Two Major Cytotoxic Withanolides from Athenaea fasciculata (Vell.) I.M.C. Rodrigues & Stehmann

Plants
Athenaea fasciculata belongs to the Solanaceae family and is a promising source of cytotoxic withanolides known as aurelianolides A and B. In the last years, the pharmacological studies of these aurelianolides on different leukemia cell lines have ...
André Mesquita Marques, Lavínia de Carvalho Brito, Maria Raquel Figueiredo   +2 more
doaj   +1 more source

Acaricidal Activity against and Essential Oil Composition of Four Species from Caatinga Biome in Northeastern Brazil

Natural Product Communications, 2011
Volatile components of essential oils from the leaves and stems of Croton jacobinensis, C. rhamnifolius, C. muscicapa and C. micans , which are medicinal plants found in the Caatinga biome of northeastern Brazil, were analyzed using GC and GC/MS.
Ilzenayde Araújo Neves, Claudio Augusto Gomes da Camara   +1 more
doaj   +1 more source

Nutraceutical Blends Promote Weight Loss, Inflammation Reduction, and Better Sleep: The Role of Faecalibacterium prausnitzii in Overweight Adults–A Double‐Blind Trial

Molecular Nutrition &Food Research, Volume 69, Issue 17, September 2025.
This study explored how a 90‐day nutraceutical blend with prebiotics, minerals, and silymarin affects the gut‐brain axis in overweight adults. Results showed improved gut microbiota, reduced inflammation, and better sleep, mood, and quality of life, suggesting a strong link between gut health and mental well‐being.
Aline Boveto Santamarina, Victor Nehmi Filho, Jéssica Alves de Freitas, Lucas Augusto Moysés Franco, Roberta Cristina Martins, Joyce Vanessa Fonseca, José Antônio Orellana Turri, Mariana Tedesco Hufnagel, Daniel Pecoraro Demarque, Bruna Fernanda Rio Branco da Silva, Arianne Fagotti Gusmão, Eloísa Helena Ribeiro Olivieri, Erica de Souza, Esther Alves de Souza, José Pinhata Otoch, Ana Flávia Marçal Pessoa   +15 more
wiley   +1 more source

Intracellular and Extracellular Efficacy of Homoisoflavone Derivatives Against Mycobacterium Tuberculosis: Progress Toward Novel Antitubercular Agents

ChemMedChem, Volume 20, Issue 14, July 18, 2025.
A series of 42 homoisoflavones were synthesized and evaluated against Mycobacterium tuberculosis (Mtb). Three derivatives showed potent inhibition of Mtb strains. Evaluation in infected macrophages revealed promising intracellular activity, where one derivative featuring a nitrofuranyl and piperidine group emerges as the most promising.
Sanderson D. Calixto, Juliane S. Falcão, Stella S. Antunes, Marlon H. Araujo, Alexandre L. B. Cunha, David R. Martins, Sarah M. R. Nascimento, Thatiana L. B. V. Simão, Elena B. Lasunskaia, Nelilma C. Romeiro, Paulo R. R. Costa, Michelle F. Muzitano, Guilherme S. Caleffi   +12 more
wiley   +1 more source

Anticorrosive activity and chemical fingerprinting of pineapple byproducts

Discover Electrochemistry
Food by-products are often considered to have no commercial value for industries and are usually discarded during processing, eventually contributing to environmental pollution. Ananas comosus (L.) Merr.
André Athayde de Figueiredo Freire, Marcelo Tadeu Gomes de Sampaio, Aline Camargo Jesus de Souza Wuillda, Ana Carolina da Silva Almeida Pereira, Mariana Vicente da Silva, Marcelo Dante Carneiro Ignácio, Eduardo Ariel Ponzio, Fernanda das Neves Costa   +7 more
doaj   +1 more source

Psoríase e produtos naturais

, 2022
A psoríase é uma doença inflamatória crónica do foro dermatológico que afeta cerca de 2-3% da população mundial. A sua etiologia não é inteiramente compreendida, no entanto, reconhece-se o seu carácter multifatorial em resultado da interações de fatores intrínsecos e extrínsecos ao organismo.
openaire   +1 more source

Electrochemistry and Antioxidant Activities of Substituted Furanyl Nitrone: The Role of the Nitro Group

ChemElectroChem, Volume 12, Issue 13, July 3, 2025.
N‐methyl‐nitroaryl‐furanyl‐nitrone (LQB‐569) suffers a 10‐electron reduction, forming a hydrazine group with two terminal hydroxylamine groups. Nitrones’ antioxidant capacity (AO), despite being very low, correlates with their oxidation profiles, and the ones able to oxidize more easily have better results on DPPH• scavenging and ferric‐reducing ...
Danyelle Cândido Santos, Débora de Souza dos Santos Costa, Paulo R. R. Costa, Ayres Guimarães Dias, Messias de Oliveira Silva, Taualia Achira Aly, Vinícius Del Colle, Jadriane Almeida Xavier, Marília O. F. Goulart, Thaissa Lúcio Silva   +9 more
wiley   +1 more source