Results 71 to 80 of about 352,044 (207)

Um método para o desenvolvimento de produtos alimentícios aplicado em uma indústria avícola [PDF]

open access: yes, 2004
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-graduação em Engenharia de ProduçãoProblema e Justificativa.
Mendez, Susana Irusta
core  

Avaliação do potencial antipsoriático de formulações tópicas contendo frações de Lacistema pubescens Mart.: um estudo in vivo

open access: yesHU Revista
Introdução: A psoríase, uma doença inflamatória crônica e imunomediada da pele, afeta aproximadamente 125 milhões de pessoas no mundo. Agentes imunossupressores são geralmente utilizados, porém podem causar efeitos colaterais locais e sistêmicos.
Josiane Mello da Silva   +4 more
doaj   +1 more source

Mechanisms Underlying Vasorelaxation Induced in Rat Aorta by Galetin 3,6-Dimethyl Ether, a Flavonoid from Piptadenia stipulacea (Benth.) Ducke

open access: yesMolecules, 2014
In this study, we investigated the relaxant action of galetin 3,6-dimethyl ether (FGAL) on rat aorta. The flavonoid relaxed both PMA‑ and phenylephrine (Phe)-induced contractions (pD2 = 5.36 ± 0.11 and 4.17 ± 0.10, respectively), suggesting the ...
Cibério L. Macêdo   +7 more
doaj   +1 more source

Produtos naturais anti - Helicobacter pylori: revisão

open access: yesRevista Ibero-Americana de Ciências Ambientais, 2018
A infecção pela bactéria Helicobacter pylori é considerada um problema de saúde pública, com intrínseca relação saúde e ambiente, a infecção bacteriana crônica mais comum no mundo, com alta prevalência em países em desenvolvimento. O uso de produtos naturais voltados a inovação medicamentosa, aumenta o interesse por novos princípios ativos a base de ...
Mariana Lenina Menezes Aleixo   +2 more
openaire   +2 more sources

Synthesis of biofuel esters catalyzed by lipase B from Candida antarctica immobilized on a magnetic lignin‐based support derived from cashew apple bagasse

open access: yesBiofuels, Bioproducts and Biorefining, Volume 19, Issue 4, Page 1165-1173, July/August 2025.
Abstract This study investigated the biosynthesis of ethyl oleate (EO), the main constituent of biodiesel, via the esterification of oleic acid with ethanol, catalyzed by Candida antarctica lipase B (CALB) immobilized on a low‐cost support derived from cashew apple bagasse (CAB) lignin.
Hilldyson Moreira Levy   +5 more
wiley   +1 more source

Avaliação da potencial atividade antimicrobiana de produtos de origem natural: estudo bioguiado de Dalbergia ecastaphyllum L. Taub [PDF]

open access: yes, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2011A pesquisa de novas substâncias com potencial antimicrobiano possui grande relevância científica, pois
Aresi, Cassandra
core  

Putatively Identified Sarmentoside-B Removes Oligomerized Amyloid Peptide from Neurons by Inhibiting mTOR and Restoring Lysosomal Function, in In Vitro Alzheimer’s Disease Model

open access: yesPharmaceutics
Background/Objectives: Alzheimer’s disease (AD) is characterized by beta-amyloid (Aβ) plaque deposition, which impairs several cellular processes, including autophagy.
Bruna Rojas Fróes   +5 more
doaj   +1 more source

In Vitro and In Silico Evaluation of Isatin‐Derived Spirooxindoles as Antituberculosis Drug Candidates

open access: yesChemical Biology &Drug Design, Volume 106, Issue 1, July 2025.
Two compounds, A16 and A17, were active against multidrug‐resistant Mycobacterium tuberculosis isolates (PT‐12 and PT‐20), overcoming key resistance mutations in katG and rpoB, while cytotoxicity assays confirmed that they are non‐toxic. A17 exhibited the highest antituberculosis activity, with molecular docking suggesting enoyl‐[acyl‐carrier‐protein ...
Fernanda Rodrigues de Lima   +11 more
wiley   +1 more source

Synthesis of Unnatural Amino Acids via β‐Aminoaldehyde C–H Arylation using HAT‐Metallaphotoredox Catalysis

open access: yesAdvanced Synthesis &Catalysis, Volume 367, Issue 9, May 6, 2025.
Abstract Unnatural amino acids play a crucial role in advancing protein engineering and drug development. In this study, we present the synthesis of a series of γ‐aryl‐keto‐α‐amino acids through the direct C−H arylation of readily accessible β‐aminoaldehydes and aryl bromides, promoted by hydrogen atom transfer combined with metallaphotoredox catalysis.
Mariana dos S. Dupim   +3 more
wiley   +1 more source

PEG‐400 Mediated N‐(Alkyl)Arylation for the Synthesis of Medicinally Relevant 4‐Aminoquinazolines

open access: yesChemistrySelect, Volume 10, Issue 15, April 17, 2025.
A new approach for quinazoline N‐(alkyl)arylation using PEG‐400 as a green solvent in microwave or conventional heating reactors presents an interesting option for synthesizing 4‐aminoquinazolines. This strategy is compatible with a variety of substituted amines and shows good tolerance for both electron‐donating and electron‐withdrawing groups, making
Gabriel de Paula Bueno   +5 more
wiley   +1 more source

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