Results 121 to 130 of about 261,938 (311)

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

Advanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu, Wen Geng, Zhi Du, Yifan Du, Di Wu, Bide Tong, Huaizhen Liang, Xingyu Zhou, Zixuan Ou, Junyu Wei, Kun Wang, Yu Song, Wenbin Hua, Yan Xu, Wencan Ke, Bingjin Wang, Cao Yang   +16 more
wiley   +1 more source

People's Perception on the Process of Professional Integration

, 2015
Although there is a tendency to associate professional integration difficulties of young people with economic crisis we face today in reality, this problem occurs since the 1970s. After almost half a century ago, that we not only have not been identified
Neagu, Gabriela
core   +1 more source

Leveraging professional learning communities in linking digital professional development and instructional integration: evidence from 16,072 STEM teachers

International Journal of STEM Education
Background Integration of digital tools and resources in STEM instruction has garnered significant attention due to its high potential. Digital professional development is identified as a pivotal factor for equipping teachers with necessary digital ...
Ji Liu, Millicent Aziku, Faying Qiang, Bin Zhang   +3 more
doaj   +1 more source

L’insertion professionnelle des personnes en situation de handicap issues de l’enseignement postsecondaire : une étude de la portée

Revue Internationale de Pédagogie de l’Enseignement Supérieur
More and more students with disabilities are graduating from post-secondary establishments without knowing their conditions of entry into professional life (Le Roux and Marcellini, 2011; Vincent, 2020).
Ruth Philion, Jesse Schnobb, Isabelle St-Pierre, Josée Grenier, Christiane Bergeron-Leclerc, Audrey Le Tellier, Caroline St-Jacques, Simon Bouisset   +7 more
doaj   +1 more source

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

Advanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng, Yanlin Guo, Liumi Jiang, Jing Luo, Yan Liu, Ziwei Yuan, Pingyang Ke, Ran Duan, Fei Xiao   +8 more
wiley   +1 more source

Teachers' perceptions of online modules to promote professional learning of ICT

, 2007
Online professional learning has the potential to be a cost effective, flexible approach that can reach large numbers of teachers. However, there are many factors that need to be evaluated in developing successful online approaches that impact on ...
Herrington, J., Reid, D., Herrington, A., Hoban, G.   +3 more
core  

16th International Conference of the Society for Information Technology and Teacher Education (SITE 2005) [PDF]

, 2005
[Abstract]: This study extends previous work on pre-service teachers'use of Information and Communication Technology (ICT) during professional experience by collecting data about intentions for ICT use prior to an experience and comparing that with use ...
Albion, Peter, Maroulis, Jerry, Redmond, Petrea   +2 more
core  

The influence of digital professional development and professional learning communities in the relationship between school digital preparedness and digital instructional integration.

PLoS ONE
Integration of digital tools and resources in STEM instruction has garnered significant attention due to its high potential. Digital professional development and professional learning communities are identified as a pivotal factor for equipping teachers ...
Stephen Kwashie Amemasor, Stephen Opoku Oppong, Benjamin Ghansah, Ben-Bright Benuwa, Mathias Agbeko   +4 more
doaj   +1 more source

3D Large‐Scale Subwavelength‐Resolution Sound Sheet Tomography Based on an Active and Programmable Circular Meta‐Array

Advanced Science, EarlyView.
A programmable 2048‐element circular ultrasound array combined with a compact acoustic lens produces a thin “sound sheet” over a large field of view, and records echoes with wide angular diversity across the ring aperture. Coherence‐enhanced beamforming converts full‐matrix data into high‐contrast tomographic slices, delivering near‐diffraction‐limited
Qiu‐De Zhang, Zi‐Bin Lin, Zhuo Chen, Zhao‐Hui Liu, Jin‐Lian He, Jun‐Jie Song, Long‐Sheng Zeng, Liang Zhou, Ming‐Yue Ding, Yu‐Gui Peng, Ming Yuchi, Xue‐Feng Zhu   +11 more
wiley   +1 more source

Integration of Professional Certifications in Business Curricula

, 2020
The purpose of the paper is to showcase integration of professional certifications into business school curricula. The reasons for such integration and logistics of doing so are discussed based on the experience of a business school in a comprehensive ...
Jacobs, Raymond, Pittenger, Khushwant K., Moss, Jacob   +2 more
core