Results 231 to 240 of about 1,243,325 (283)

Sex as a biological variable in nonclinical studies: Bridging scientific rigor, animal welfare, and regulatory expectations

Animal Models and Experimental Medicine, EarlyView.
Sex as a biological variable (SABV) is a critical determinant of pharmacokinetics, pharmacodynamics, and toxicity in nonclinical studies. This review highlights how inappropriate neglect of sex differences compromises animal welfare, scientific reproducibility, and regulatory compliance.
Kenta Onuma, Masaki Watanabe, Nobuya Sasaki   +2 more
wiley   +1 more source

The dual pathways of emotional labor in psychiatric nursing: the adaptive and maladaptive emotional strategies. [PDF]

Front Psychiatry
Huang G, Zheng Y, Shen G, Wang H, Wang L.   +4 more
europepmc   +1 more source

Cancer therapy‐induced ototoxicity: Current challenges and emerging management strategies

Animal Models and Experimental Medicine, EarlyView.
This review comprehensively examines the key risk factors for cancer therapy‐induced ototoxicity, including cumulative drug dose, genetic susceptibility, and combined treatment regimens. It highlights current challenges in ototoxicity monitoring, such as insufficient timeliness and limited clinical adoption, and advocates for standardized auditory ...
Yuqi Huang, Baoying Xu, Xinru Chen, Yu Chen, Dehong Yu   +4 more
wiley   +1 more source

Patterns of Alarm Fatigue and Their Predictors Among Nurses in Intensive Care Units: A Latent Profile Analysis. [PDF]

Nurs Health Sci
Yang F, Tai R, Yu Q, Qi Q, Wang Q, Pu Y, Fang F.   +6 more
europepmc   +1 more source

Alzheimer's Disease Co‐Pathology and Cognitive Impairment in Amyotrophic Lateral Sclerosis

Annals of Neurology, EarlyView.
Objectives Amyotrophic lateral sclerosis (ALS) and Alzheimer's disease (AD) share neuropathological features, including tau, amyloid, and TDP‐43 pathology. This study investigated whether AD‐related pathological changes are associated with cognitive impairment ALS. Methods Cerebrospinal fluid (CSF total‐tau, phosphorylated‐tau, beta‐amyloid) and plasma
Elisabeth Kasper, Annaliis Lehto, Alexandra Jürs, Nina Nordmann, Oliver Peters, Julian Hellmann, Josef Priller, Eike Jakob Spruth, Gabor C. Petzold, Ina Voigt, Patrick Weydt, Sarah Bernsen, Elisabeth Dinter, Björn Falkenburger, René Günther, Emrah Düzel, Wenzel Glanz, Matthis Synofzik, Lukas Beichert, Annika Spottke, Michael Wagner, Frederic Brosseron, Matthias C. Schmid, Annett Halle, Jochen Herms, Anja Schneider, Stefan Teipel, Johannes Prudlo, Manuela Neumann, Andreas Hermann   +29 more
wiley   +1 more source

Development of an interdisciplinary consensus statement for assessing fitness for work at heights in the South African construction industry: a virtual Modified Nominal Group Technique study. [PDF]

J Occup Med Toxicol
Swart L, Buys T, Claassen N.
europepmc   +1 more source

Relationship Between Reflective Practice and Caring Behaviors Among Psychiatric Nurses: A Latent Profile Analysis. [PDF]

Risk Manag Healthc Policy
Ren Y, Li J, Lin X, Luo S.
europepmc   +1 more source

Leadership Styles Among Nurses: A Cross-Sectional Analysis Within the Full Range Leadership Framework. [PDF]

Nurs Rep
Moreira C, Moutinho P, Alves P, Mota L.
europepmc   +1 more source

Latent profile analysis of compassion fatigue and its relationship with humanistic care ability among psychiatric nurses in Henan Province. [PDF]

Front Public Health
Zhang J, Yang M, Yan F, He S, Shang C, Zhang Y.   +5 more
europepmc   +1 more source

Motivations for hospice palliative care volunteerism and its associated factors among Chinese nursing undergraduates: a latent profile study. [PDF]

BMC Palliat Care
Wang J, Liu L, Wang Y, Wang D, Song Y, Zhan K, Sun X, Wang J, Tong H.   +8 more
europepmc   +1 more source