Results 121 to 130 of about 11,882,175 (245)

A Glucose Metabolism‐Modulatory Nanobiohybrid Vaccine Platform Promotes Anti‐Tumor Immunity by Orchestrating Autophagy‐Dependent Cross‐Presentation and H2S‐Enhanced NLRP3 Inflammasome Signaling

Advanced Science, EarlyView.
A nanobiohybrid vaccine was designed by constructing a hydrogen‐bonded organic framework coencapsulated with glucose oxidase (GOx) and tumor antigens. This nanobiohybrid vaccine executed a GOx‐catalyzed enzyme reaction that disrupted glucose metabolism and induced redox imbalance in dendritic cells, leading to autophagy‐dependent antigen cross ...
Weidong Wang, Yimin Gong, Jianing Li, Tianze Wu, Mingli Deng, Yannan Yang   +5 more
wiley   +1 more source

Exploring the Process of Professional Role Redefinition Towards Recovery-Oriented Care Through Joint Crisis Plans in Japan: A Qualitative Study Using the Modified Grounded Theory Approach. [PDF]

Healthcare (Basel)
Ebihara M, Tamura T, Masukawa N, Omiya T, Ando K.   +4 more
europepmc   +1 more source

Stakeholder Perception of the Professional Role and Competence of Swedish Dental Hygienists: A Questionnaire and Interview Study. [PDF]

J Int Soc Prev Community Dent, 2020
Erdenborg J, Malmqvist S, Bjurshammar N, Johannsen G, Hultin M, Johannsen A.   +5 more
europepmc   +1 more source

SOX5 Orchestrates Malignant Evolution via Promoter‐Centric Chromatin Remodeling in MYC‐Driven B‐Cell Lymphoma

Advanced Science, EarlyView.
In MYC‐enforced B‐cell lymphoma, SOX5 occupies promoter‐proximal regulatory regions and is associated with reduced chromatin accessibility at the PCNP locus. PCNP repression promotes proliferative remodeling by limiting apoptosis and cell‐cycle restraint.
Yiyou Mao, Zhenyuan Jia, Xiao‐Qin Mu, Ruilin Wang, Jianli Ma, Qingyuan Zhang, Yuwei Deng   +6 more
wiley   +1 more source

An international portrait of pharmacists' professional role identities: A Q-methodology innovative study. [PDF]

Explor Res Clin Soc Pharm
Watson KE, Schindel TJ, Meilianti S, Tsuyuki RT, Al Hamarneh YN.   +4 more
europepmc   +1 more source

A Supramolecular Thermal Switch for Precision Pyroptosis via Host−Guest Recognition and Electrostatic Interactions

Advanced Science, EarlyView.
A supramolecular pyroptotic thermal switch encapsulates I3− within β‐cyclodextrin (β‐CD) and undergoes CaCO3 mineralization. Upon lysosomal acidification, CaCO3 is degraded, releasing Ca2+ and I3−. Concurrently, BODIPY activation converts I3− into I2, inducing oxidative stress and Ca2+ overload, which together trigger caspase‐3/GSDME‐mediated ...
Dan Wu, Jie Zhou, Yibin Cao, Kunmin Ping, Borui Zhao, Yanrong Yang, Chunyang Yu, Xinyang Yu, Shaolong Qi   +8 more
wiley   +1 more source

Professional Role Transition in Nursing: Leveraging Transition Theory to Mitigate the Current Human Resource Crises. [PDF]

Healthcare (Basel)
Akomeng Aryeequaye S, Corneau K, Duchscher JE.   +2 more
europepmc   +1 more source

Molecular Dynamics‐Guided Sterol Engineering of mRNA‐Lipid Nanoparticles Reprograms Biodistribution and Enhances Spleen‐Selective Immunity

Advanced Science, EarlyView.
Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon, Seo‐Hyeon Bae, Jungyong Ji, Jisun Lee, Hosam Choi, Min‐Ho Kang, Sang‐In Park, Hyemin Kim, Nakyung Lee, Hajin Lee, Seonghoon Kim, Jungmin Kim, Subin Yoon, Seonghyun Lee, Seongje Cho, Dahyeon Ha, Ayoung Oh, Sohee Jo, Huijeong Choi, Yeeun Lee, Sowon Lee, Hyo‐Jung Park, Gitak Nam, Jisu Shin, Yujin Kang, Wonpil Im, Kiyoun Lee, Jae‐Hwan Nam   +27 more
wiley   +1 more source

Generative AI's healthcare professional role creep: a cross-sectional evaluation of publicly accessible, customised health-related GPTs. [PDF]

Front Public Health
Chu B, Modi ND, Menz BD, Bacchi S, Kichenadasse G, Paterson C, Kovoor JG, Ramsey I, Logan JM, Wiese MD, McKinnon RA, Rowland A, Sorich MJ, Hopkins AM.   +13 more
europepmc   +1 more source

Understanding health professional role integration in complex adaptive systems: a multiple-case study of physician assistants in Ontario, Canada. [PDF]

BMC Health Serv Res, 2020
Burrows KE, Abelson J, Miller PA, Levine M, Vanstone M.   +4 more
europepmc   +1 more source