Results 141 to 150 of about 926,824 (309)

القائمة السورية للأعراض assistant Professor associate Professor Professor associate Professor Professor

القائمة السورية للأعراض ملخص مع ازدياد انتشار الأعراض النفسية والجسدية يحتاج المتخصصون النفسيون والأطباء بتخصصاتهم المختلفة إلى أدوات سهلة التطبيق وصادقة تتيح لهم تحديد مدى انتشار الأعراض المرضية وتفاقمها أو تراجعها. وقد هدفت هذه الدراسة إلى إعداد قائمة لتحديد الأعراض والشكاوى المرضية التي يعاني منها المرضى أو الذين يعانون من شكاوى نفسية نظراً لأهمية ...
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Concepções de futuros professores de ciências físico-químicas sobre a utilização de actividades laboratoriais [PDF]

, 2000
De acordo com uma perspectiva construtivista do ensino e da aprendizagem, será de esperar que os futuros professores de Ciências Físico-Químicas tenham ideias prévias acerca do modo como esta disciplina deve ser ensinada e que essas ideias influenciem ...
Afonso, Ana Sofia, Leite, Laurinda
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ELABELA Targets Mitochondria to Modulate Heart Development

Advanced Science, EarlyView.
The role of peptide ELABELA (ELA) in cardiomyocyte apoptosis and congenital heart disease (CHD) is unclear. ELA deficiency caused cardiomyocyte apoptosis and CHD. A novel ELA‐APJ‐AKT‐BCL2/BAX axis in regulating mitochondrial function and contributing to CHD pathogenesis was established.
Jian Wang, Qingjie Wang, Zhikang Xu, Shuang Zhou, Yue Zhou, Junjie Yang, Lingfeng Tong, Zhuo Meng, Mei Yang, Wen Zhao, Tie Yang, Hualin Wang, Jun Zhang, Rubin Tan, Lei Wang, Yuqiang Huang, Bin Zhou, Sun Chen, Bing Zhang, Jinxiang Yuan, Jianyuan Zhao, Alex F. Chen, Kun Sun   +22 more
wiley   +1 more source

التقنية والمسألة الأخلاقية assistant Professor associate Professor Professor associate Professor Professor

شهد العالم في نهايات القرن العشرين وبداية القرن الحالي ثورة تقنية غير مسبوقة قلبت الكثير من التصورات القائمة حتى الآن عن العالم من حولنا. وما كان غير قابل للتصور أصبح الآن من البديهيات في تعاملاتنا اليومية، وأصبح ما يحدث في أي مكان من العالم يؤثر على أصغر بقعة على الأرض.
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METODOLOGIAS DE ENSINO-APRENDIZAGEM: UMA ABORDAGEM SOB A PERCEPÇÃO DOS ALUNOS [PDF]

, 2014
O objetivo do estudo consiste em verificar quais os métodos de ensino se mostram mais eficazes em relação à aprendizagem, na percepção dos alunos e, destes, quais têm sido mais utilizados pelos professores.
Brighenti, Josiane, Souza, Taciana Rodrigues de   +1 more
core  

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
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الحاضر الغائب Editor of ArabiXiv assistant Professor associate Professor Professor associate Professor Professor

تغير وسائل الإعلام واقعنا وعلاقاتنا حيث نعيش بشكل متزايد في عالم، هو في الحقيقة "في مكان آخر". فالتلفاز والراديو و الفيديو والحاسب والانترنت والبريد الإلكتروني يقربون منا الغياب، ويعمون عن الواقع المباشر.
Khaled Moustafa, Samer Rudwan
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Avaliação de conteúdo na disciplina de matemática no ensino médio [PDF]

, 2005
TCC (graduação) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Curso de Matemática.A educação está passando por momentos difíceis em nosso País, e merece atenção dos órgãos competentes.
Santos, Cristina dos
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PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source