Results 171 to 180 of about 907,518 (291)
During pupal metamorphosis and starvation, elevated 20‐hydroxyecdysone (20E) and suppressed insulin trigger Forkhead box O (FOXO) nuclear translocation, enhancing miR‐375‐3p expression. This downregulates fatty acid synthase (FASN) and Relish, promoting lipid breakdown for energy while prioritizing antioxidant responses over immune functions to support
Peng Chen +10 more
wiley +1 more source
A Natural Sweetener‐inducible Genetic Switch Controls Therapeutic Protein Expression in Mammals
This study develops a natural sweetener, the psicose‐inducible transgene expression (PURE) system based on an Agrobacterium tumefaciens–derived transcriptional repressor PsiR. The PURE system is highly specific to psicose, being insensitive to other sugars and structurally similar molecules.
Longliang Qiao +16 more
wiley +1 more source
Actions on childhood voice in public schools: a scoping review. [PDF]
Sebastião LT +4 more
europepmc +1 more source
KDM4A Erases the H3R17me2a Mark, Facilitating Chromosome Condensation
This study reveals a reversible histone modification switch governing chromosome condensation during mitosis. PKCα‐activated KDM4A removes H3R17me2a, permitting Suv39h1‐driven H3K9me3 deposition. This epigenetic transition recruits the chromosomal passenger complex and triggers Aurora B‐dependent H3S10 phosphorylation, coordinating chromatin remodeling
Yena Cho +6 more
wiley +1 more source
تهدف التربية الصحية إلى دفع الناس من جميع الاعمار إلى تحمل المسؤولية فيما يتعلق بصحتهم الشخصية. وبهذا فإن الهدف يتمثل في التحلل من انماط السلوك الخطر وبناء انماط سلوك صحي بما في ذلك الاحتفاظ بأنماط السلوك التي تم اكتسابها والتي هي داعمة للصحة. وتتميز هذه العملية بصعوبات كثيرة ولا تحقق على ما يبدو، لدى المعنيين، النجاح المرغوب. فقد ظهر أن كثيرا من انماط
openaire +1 more source
People value solitude in varying degrees. Theories and studies suggest that people’s appreciation of solitude varies considerably across persons (e.g., an introverted person may value solitude more than an extraverted person), and solitude experiences (i.e., on average, people may value some functions of solitude, e.g., privacy, more than other ...
Dongning Ren +3 more
openaire +1 more source
Anatomical Behaviour of the Phrenic Nerve and Innervation of the Diaphragm in the Maned Wolf (Chrysocyon brachyurus). [PDF]
do Nascimento BC +10 more
europepmc +1 more source
Low Back Pain in Medical Students and Professors During the Pandemic: Retrospective Cohort Study. [PDF]
Mattos AF +3 more
europepmc +1 more source

