FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
Evolution of nucleic acid amplification testing across Canada as observed through the Canadian Laboratory Response Network's SARS-CoV-2 Proficiency Test Program, May 2020 to June 2021. [PDF]
Can Commun Dis Rep, 2023 Ranadheera C, Antonation K, Corbett C.
europepmc +1 more source
An early warning system for multivariate time series with sparse and non-uniform sampling [PDF]
, 1962 In this paper we propose a new early warning test statistic, the ratio of deviations (RoD), which is defined to be the root mean squared of successive differences divided by the standard deviation.
Roberts, Andrew, Are, Sasanka
core +7 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Candidate Proficiency Test Chemicals to Address Industrial Chemical Applicability Domains for in vitro Human Cytochrome P450 Enzyme Induction. [PDF]
Front Toxicol, 2022 Jacobs MN, Kubickova B, Boshoff E.
europepmc +1 more source
The Analysis of German Language Students’ Error: A Case Study of the Results of the Schreiben German Proficiency Test (UKBJ) at UNESA [PDF]
, 2023 Dwi Imroatu Julaikah +5 more
openalex +1 more source
What test scores can and cannot tell us about the quality of our schools. [PDF]
"What Test Scores Can and Cannot Tell Us about the Quality of Our Schools," by Ted Crone, recognizes that how to best judge the quality of our schools is a thorny issue.
Theodore M. Crone
core
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Grade-Related Differential Item Functioning in General English Proficiency Test-Kids Listening. [PDF]
Front Psychol, 2021 Liao L, Yao D.
europepmc +1 more source