Results 71 to 80 of about 93,844 (259)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Evaluation of an Adaptive Learning Technology in a First-year Extended Curriculum Programme Physics course

open access: yesSouth African Computer Journal, 2017
Personalised, adaptive online learning platforms that form part of web-based proficiency tests play a major role in the improvement of the quality of learning in physics and assist learners in building proficiency, preparing for tests and using their ...
Moses Mushe Basitere, Eunice Ndeto Ivala
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The Content Analysis, the Presentation, and the Instrument Readability of Indonesian Proficiency Test

open access: yesAsian Journal of Assessment in Teaching and Learning, 2017
The research has aim to describe the result of the content analysis, the presentation, and the instrument readability of the Indonesian proficiency test. The method used in the research was the qualitative descriptive research method.
Laili Etika Rahmawati   +3 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

THE IELTS READING TEST: A REVIEW ON ITS DEVELOPMENT AND LANGUAGE TEST PERFORMANCE

open access: yesGetsempena English Education Journal, 2016
International English Language Testing System (IELTS) is regarded as one of proficiency tests that is generally accepted by British and Australian universities  in selecting and screening  overseas students.
Yuliar Masna
doaj   +1 more source

[Results of the Proficiency Test for Diagnostic Testing of Notifiable Infectious Diseases]. [PDF]

open access: yesJugan Geongang Gwa Jilbyeong, 2023
Park OK, Lee SG, Park JS, Kim GJ.
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Development of a national proficiency test for SARS-CoV-2 detection by PCR in Colombia. [PDF]

open access: yesJ Glob Health, 2023
Dávila SL   +5 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy