Results 11 to 20 of about 333,801 (297)

Accurate and robust phylogeny estimation based on profile distances: a study of the Chlorophyceae (Chlorophyta)

open access: yesBMC Evolutionary Biology, 2004
Background In phylogenetic analysis we face the problem that several subclade topologies are known or easily inferred and well supported by bootstrap analysis, but basal branching patterns cannot be unambiguously estimated by the usual methods (maximum ...
Rahmann Sven   +3 more
doaj   +3 more sources

Optimal Experimental Design Based on Two-Dimensional Likelihood Profiles

open access: yesFrontiers in Molecular Biosciences, 2022
Dynamic behavior of biological systems is commonly represented by non-linear models such as ordinary differential equations. A frequently encountered task in such systems is the estimation of model parameters based on measurement of biochemical compounds.
Tim Litwin   +8 more
doaj   +1 more source

Generalised likelihood profiles for models with intractable likelihoods

open access: yesStatistics and Computing, 2023
Likelihood profiling is an efficient and powerful frequentist approach for parameter estimation, uncertainty quantification and practical identifiablity analysis. Unfortunately, these methods cannot be easily applied for stochastic models without a tractable likelihood function.
David J. Warne   +4 more
openaire   +4 more sources

Estimating uncertainty of model parameters obtained using numerical optimisation [PDF]

open access: yesModeling, Identification and Control, 2019
Obtaining accurate models that can predict the behaviour of dynamic systems is important for a variety of applications. Often, models contain parameters that are difficult to calculate from system descriptions.
Ole Magnus Brastein   +3 more
doaj   +1 more source

Bayesian Inference in Extremes Using the Four-Parameter Kappa Distribution

open access: yesMathematics, 2020
Maximum likelihood estimation (MLE) of the four-parameter kappa distribution (K4D) is known to be occasionally unstable for small sample sizes and to be very sensitive to outliers.
Palakorn Seenoi   +2 more
doaj   +1 more source

Profile likelihood biclustering

open access: yesElectronic Journal of Statistics, 2020
Biclustering, the process of simultaneously clustering the rows and columns of a data matrix, is a popular and effective tool for finding structure in a high-dimensional dataset. Many biclustering procedures appear to work well in practice, but most do not have associated consistency guarantees.
Flynn, Cheryl, Perry, Patrick
openaire   +3 more sources

Likelihood-based estimation and prediction for a measles outbreak in Samoa

open access: yesInfectious Disease Modelling, 2023
Prediction of the progression of an infectious disease outbreak is important for planning and coordinating a response. Differential equations are often used to model an epidemic outbreak's behaviour but are challenging to parameterise. Furthermore, these
David Wu   +4 more
doaj   +1 more source

PROLIFIC: A Fast and Robust Profile-Likelihood-Based Muscle Onset Detection in Electromyogram Using Discrete Fibonacci Search

open access: yesIEEE Access, 2020
A stochastic scheme, namely, PLM-Lap, has recently been propounded, which relies on the profile likelihood (PL) constructed with a Laplace distribution for estimating muscle activation onsets (MAOs) in surface electromyographic (sEMG) data.
Easter S. Suviseshamuthu   +4 more
doaj   +1 more source

Profile Maximum Likelihood Estimation of Single-Index Spatial Dynamic Panel Data Model

open access: yesMathematics, 2023
In this paper, the spatial dynamic panel data (SDPD) model is extended to the single-index spatial dynamic panel data (Si-SDPD) model by introducing a nonlinear connection function to reflect the interaction between explanatory variables.
Mengqi Zhang, Boping Tian
doaj   +1 more source

Assessing parameter identifiability for Dynamic Causal Modelling of fMRI data

open access: yesFrontiers in Neuroscience, 2015
Deterministic dynamic causal modelling (DCM) for fMRI data is a sophisticated approach to analyse effective connectivity in terms of directed interactions between brain regions of interest. To date it is difficult to know if acquired fMRI data will yield
Carolin eArand   +6 more
doaj   +1 more source

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