Results 61 to 70 of about 1,311,331 (302)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Testing adiabatic contraction of dark matter in fossil group candidates

, 2010
We present deep XMM observations and ESO WFI optical imaging of two X-ray-selected fossil group candidates, RXCJ0216.7-4749 and RXCJ2315.7-0222. Using the X-ray data, we derive total mass profiles under the hydrostatic equilibrium assumption. The central
Allen, Arnaud, Arnouts, Baade, Barnes, Bartelmann, Bertin, Blumenthal, Bruzual, Bryan, Buote, Cappellari, Chabrier, Croston, Croston, D. Pierini, de Vaucouleurs, Duffy, Duffy, E. D'Onghia, Eggen, G. W. Pratt, Gastaldello, Gavazzi, Gnedin, Grimm, Humphrey, J. Démoclès, Jing, Jones, Khosroshahi, Kravtsov, Kron, Kroupa, Landolt, Lewis, M. Arnaud, Magorrian, Mamon, Markevitch, Mazzotta, Mignano, Moraux, Nagai, Navarro, Navarro, Neumann, Paresce, Pointecouteau, Ponman, Poole, Pratt, Pratt, Pratt, Pratt, Rasmussen, Renzini, S. Zibetti, Salpeter, Sand, Schlegel, Schmidt, Sun, Tissera, van der Marel, Vikhlinin, Vikhlinin, Vikhlinin, Voit, von Benda-Beckmann, Zappacosta, Zibetti, Zibetti   +72 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Features of Design and Production of Planetary Gears in the Belarus Mobile Machines

Механика машин, механизмов и материалов, 2010
The basic requirements to the planetary transfers, used in heavy dumpers, lorries, tractors and other machines made in Belarus are formulated. Ways of improvement of quality and perfection of manufacture of planetary transfers are planned.
V.E. Antoniuk , P.L. Mariev , Pawlowski V.Ja.   +2 more
doaj  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

METHOD FOR MODIFYING PROFILE OF CYCLOIDAL WHEEL CONSIDERING COMPENSATION FOR ELASTIC DEFORMATION

Jixie qiangdu, 2020
Considering the influence of elastic deformation on the profile of the cycloid,a cycloid profile modification method for compensating elastic deformation is proposed.Based on the theory of cycloid profile modification,the coordinates of the meshing point
QIN ZhengZheng, WANG Quan, ZHAO DaXing, WANG Jun, ZENG LiLei   +4 more
doaj  

Mesh stiffness calculation of helical gears with profile modification

The Journal of Engineering, 2018
Time-varying contact line and mesh stiffness are important parameters for dynamic investigation of helical gear pair with profile modification; however, the calculation methods of the time-varying mesh with high accuracy and high efficiency are also very
Yu Wang, Yimin Shao, Zaigang Chen, Minggang Du, Huifang Xiao   +4 more
doaj   +1 more source

Influence of linear profile modification and loading conditions on the dynamic tooth load and stress of high contact ratio gears [PDF]

A computer simulation for the dynamic response of high-contact-ratio spur gear transmissions is presented. High contact ratio gears have the potential to produce lower dynamic tooth loads and minimum root stress but they can be sensitive to tooth profile
Lee, Chinwai, Lin, Hsiang Hsi, Oswald, Fred B., Townsend, Dennis P.   +3 more
core   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source