Results 1 to 10 of about 708,299 (262)

Cyclosporine A inhibits MRTF‐SRF signaling through Na+/K+ ATPase inhibition and actin remodeling

open access: yesFASEB BioAdvances, 2019
Calcineurin inhibitors (CNI) are the pillars of immunosuppression in transplantation. However, they display a potent nephrotoxicity whose mechanisms remained widely unsolved.
Bastien Burat   +7 more
doaj   +1 more source

Bifidobacterial Distribution Across Italian Cheeses Produced from Raw Milk

open access: yesMicroorganisms, 2019
Cheese microbiota is of high industrial relevance due to its crucial role in defining the organoleptic features of the final product. Nevertheless, the composition of and possible microbe−microbe interactions between these bacterial populations ...
Christian Milani   +11 more
doaj   +1 more source

Plasma- and Saliva Exosome Profile Reveals a Distinct MicroRNA Signature in Chronic Periodontitis

open access: yesFrontiers in Physiology, 2020
Chronic periodontitis (CP) is an oral cavity disease arising from chronic inflammation of the periodontal tissues. Exosomes are lipid vesicles that are enriched in specific microRNAs (miRNAs), potentially providing a disease-specific diagnostic signature.
Nik Nur Syazana Nik Mohamed Kamal   +3 more
doaj   +1 more source

FFAS03: a server for profile-profile sequence alignments [PDF]

open access: yesNucleic Acids Research, 2005
The FFAS03 server provides a web interface to the third generation of the profile-profile alignment and fold-recognition algorithm of fold and function assignment system (FFAS) [L. Rychlewski, L. Jaroszewski, W. Li and A. Godzik (2000), Protein Sci., 9, 232-241].
Lukasz Jaroszewski   +4 more
openaire   +4 more sources

Profiling–UD: a Tool for Linguistic Profiling of Texts [PDF]

open access: yes, 2020
In this paper, we introduce Profiling–UD, a new text analysis tool inspired to the principles of linguistic profiling that can support language variation research from different perspectives. It allows the extraction of more than 130 features, spanning across different levels of linguistic description.
Dominique Brunato   +4 more
openaire   +3 more sources

Optimized murine sample sizes for RNA sequencing studies revealed from large scale comparative analysis

open access: yesNature Communications
Determining the appropriate sample size (N) for bulk RNA sequencing experiments is critical for obtaining reliable results. We show in two N = 30 profiling studies, comparing wild-type mice and mice in which one copy of a gene has been deleted, the N ...
Gabor Halasz   +7 more
doaj   +1 more source

Santé et Big Data : l’Etat et les individus, impuissants face aux pouvoirs des réseaux

open access: yesL'Espace Politique, 2017
The use of Internet and of the social networks, lead the users to share data concerning their private life and their health. The consultation of many sites, the use of smartphones or computers leaves numerous traces on networks which are logged and ...
Joël Colloc
doaj   +1 more source

Profiling of Genetic Mutations among Adult Filipino Patients Diagnosed with Acute Myeloid Leukemia using Fluorescence In Situ Hybridization from 2014 to 2021

open access: yesPhilippine Journal of Pathology, 2023
Introduction. Among patients with Acute Myeloid Leukemia (AML), the karyotype at diagnosis is an important prognostic indicator for predicting outcomes.
Aaron Pierre Calimag   +1 more
doaj   +1 more source

Rationally co-targeting divergent pathways in KRAS wild-type colorectal cancers by CANscript technology reveals tumor dependence on Notch and Erbb2

open access: yesScientific Reports, 2017
KRAS mutation status can distinguish between metastatic colorectal carcinoma (mCRC) patients who may benefit from therapies that target the epidermal growth factor receptor (EGFR), such as cetuximab.
Nilesh Brijwani   +10 more
doaj   +1 more source

Profiles of Permutations [PDF]

open access: yesThe Electronic Journal of Combinatorics, 2009
This paper develops an analogy between the cycle structure of, on the one hand, random permutations with cycle lengths restricted to lie in an infinite set $S$ with asymptotic density $\sigma$ and, on the other hand, permutations selected according to the Ewens distribution with parameter $\sigma$.
openaire   +3 more sources

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