Results 11 to 20 of about 704,038 (263)

MLPAnalyzer: Data Analysis Tool for Reliable Automated Normalization of MLPA Fragment Data

open access: yesCellular Oncology, 2008
Background: Multiplex Ligation dependent Probe Amplification (MLPA) is a rapid, simple, reliable and customized method for detection of copy number changes of individual genes at a high resolution and allows for high throughput analysis.
Jordy Coffa   +5 more
doaj   +1 more source

Neuroprotective Effect of Catalpol via Anti-Oxidative, Anti-Inflammatory, and Anti-Apoptotic Mechanisms

open access: yesFrontiers in Pharmacology, 2020
Neuroinflammation and neuro-oxidative damage are now considered to be key factors in the neurological diseases. Therefore, it is important to study anti-inflammatory and neuroprotective agents.
Chunjing Yang   +11 more
doaj   +1 more source

Spatial differences in genetic diversity and northward migration suggest genetic erosion along the boreal caribou southern range limit and continued range retraction

open access: yesEcology and Evolution, 2019
With increasing human activities and associated landscape changes, distributions of terrestrial mammals become fragmented. These changes in distribution are often associated with reduced population sizes and loss of genetic connectivity and diversity (i ...
Laura M. Thompson   +3 more
doaj   +1 more source

Scoring profile‐to‐profile sequence alignments [PDF]

open access: yesProtein Science, 2004
AbstractSequence alignment profiles have been shown to be very powerful in creating accurate sequence alignments. Profiles are often used to search a sequence database with a local alignment algorithm. More accurate and longer alignments have been obtained with profile‐to‐profile comparison.
Guoli, Wang, Roland L, Dunbrack
openaire   +2 more sources

Antioxidant Activity of Three Honey Samples in relation with Their Biochemical Components

open access: yesJournal of Analytical Methods in Chemistry, 2013
The antioxidant activities based on the free radical scavenging, reducing power, and bleaching inhibition were investigated for the three commonly used honeys in Malaysia, namely, tualang, gelam, and acacia honey.
Lee Suan Chua   +3 more
doaj   +1 more source

Assessment of local tissue responses to subcutaneous implantation of Polyetheretherketone and Polymethyl methacrylate-based materials [PDF]

open access: yesScripta Medica
Background/Aim: In surgical dentistry, maxillofacial surgery and traumatology, bone tissue regeneration is one of the most pressing challenges.
Demyashkin Grigory   +7 more
doaj   +1 more source

ASF1B Promotes Oncogenesis in Lung Adenocarcinoma and Other Cancer Types

open access: yesFrontiers in Oncology, 2021
Anti-silencing function 1B histone chaperone (ASF1B) is known to be an important modulator of oncogenic processes, yet its role in lung adenocarcinoma (LUAD) remains to be defined. In this study, an integrated assessment of The Cancer Genome Atlas (TCGA)
Wencheng Zhang   +5 more
doaj   +1 more source

HPLC-DPPH Screening Method for Evaluation of Antioxidant Compounds in Species

open access: yesNatural Product Communications, 2016
Corylus avellana L., C. colurna L. and C. maxima Mill. have been used in traditional medicine for a long time for the treatment of various diseases, such as phlebitis, varicose veins, haemorrhoidal symptoms and eczema.
Eszter Riethmüller   +5 more
doaj   +1 more source

Cardiovascular Protection by ApoE and ApoE-HDL Linked to Suppression of ECM Gene Expression and Arterial Stiffening

open access: yesCell Reports, 2012
Arterial stiffening is a risk factor for cardiovascular disease, but how arteries stay supple is unknown. Here, we show that apolipoprotein E (apoE) and apoE-containing high-density lipoprotein (apoE-HDL) maintain arterial elasticity by suppressing the ...
Devashish Kothapalli   +14 more
doaj   +1 more source

Bifidobacterial Distribution Across Italian Cheeses Produced from Raw Milk

open access: yesMicroorganisms, 2019
Cheese microbiota is of high industrial relevance due to its crucial role in defining the organoleptic features of the final product. Nevertheless, the composition of and possible microbe−microbe interactions between these bacterial populations ...
Christian Milani   +11 more
doaj   +1 more source

Home - About - Disclaimer - Privacy