Results 11 to 20 of about 5,008,337 (326)
GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses
Nucleic Acids Res., 2017 Tremendous amount of RNA sequencing data have been produced by large consortium projects such as TCGA and GTEx, creating new opportunities for data mining and deeper understanding of gene functions.
Zefang Tang +5 more
semanticscholar +1 more source
Frontiers in Genetics, 2016 Epigenetics is a rapidly developing field focused on deciphering chemical fingerprints that accumulate on human genomes over time. As the nascent idea of precision medicine expands to encompass epigenetic signatures of diagnostic and prognostic relevance,
Adam G. Marsh +4 more
doaj +1 more source
GenomeScope 2.0 and Smudgeplot for reference-free profiling of polyploid genomes
Nature Communications, 2020 An important assessment prior to genome assembly and related analyses is genome profiling, where the k-mer frequencies within raw sequencing reads are analyzed to estimate major genome characteristics such as size, heterozygosity, and repetitiveness ...
T. Ranallo-Benavidez +4 more
semanticscholar +1 more source
Spatial epigenome–transcriptome co-profiling of mammalian tissues
Nature, 2023 The authors present two technologies for spatially resolved, genome-wide, joint profiling of the epigenome and transcriptome by cosequencing chromatin accessibility and gene expression, or histone modifications and gene expression on the same tissue ...
Di Zhang +22 more
semanticscholar +1 more source
Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences
Nature Biotechnology, 2013 Profiling phylogenetic marker genes, such as the 16S rRNA gene, is a key tool for studies of microbial communities but does not provide direct evidence of a community's functional capabilities.
M. Langille +11 more
semanticscholar +1 more source
bioRxiv, 2020 Culture-independent analyses of microbial communities have advanced dramatically in the last decade, particularly due to advances in methods for biological profiling via shotgun metagenomics.
F. Beghini +15 more
semanticscholar +1 more source
Spatial profiling technologies illuminate the tumor microenvironment.
Cancer Cell, 2023 The tumor microenvironment (TME) is composed of many different cellular and acellular components that together drive tumor growth, invasion, metastasis, and response to therapies.
O. Elhanani, Raz Ben-Uri, Leeat Keren
semanticscholar +1 more source
Frontiers in Pharmacology, 2020 Neuroinflammation and neuro-oxidative damage are now considered to be key factors in the neurological diseases. Therefore, it is important to study anti-inflammatory and neuroprotective agents.
Chunjing Yang +11 more
doaj +1 more source
Slanted hole array beam profiler (SHArP)—a high-resolution portable beam profiler based on a linear aperture array [PDF]
, 2006 We demonstrate a novel high-resolution portable beam profiler based on a slanted linear array of small apertures, termed a slanted hole array beam profiler (SHArP). The apertures are directly fabricated on a metal-coated CMOS imaging sensor.
Cui, Xiquan +6 more
core +1 more source
Massively parallel digital transcriptional profiling of single cells
Nature Communications, 2016 Characterizing the transcriptome of individual cells is fundamental to understanding complex biological systems. We describe a droplet-based system that enables 3′ mRNA counting of tens of thousands of single cells per sample.
Grace X. Y. Zheng +34 more
semanticscholar +1 more source