Results 91 to 100 of about 3,212,771 (303)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
MIRCIM 2025: Ten Years of Scientific Dialogue in Evidence-Based Medicine
Львівський клінічний вісникThe 10th McMaster International Review Course in Internal Medicine (MIRCIM 2025), held in Kraków, Poland, confirmed its status as a high-impact scientific forum promoting evidence-based medical practice. With over 100 speakers from more than 40 countries,
T. Nehrych +6 more
doaj +1 more source
A General Theory of Sample Complexity for Multi-Item Profit Maximization
, 2018 The design of profit-maximizing multi-item mechanisms is a notoriously challenging problem with tremendous real-world impact. The mechanism designer's goal is to field a mechanism with high expected profit on the distribution over buyers' values ...
Balcan, Maria-Florina +2 more
core
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Financial Profit: Profit from Production and Profit upon Alienation [PDF]
Financial profit is prevalent in contemporary capitalist economies, yet its nature and sources remain unclear. In classical political economy, and for Marx, profit is conceptualised either as a fresh flow of value (profit from production) or as a share ...
Costas Lapavitsas, Iren Levina
core
Balancing the Tradeoff between Profit and Fairness in Rideshare Platforms During High-Demand Hours
, 2019 Rideshare platforms, when assigning requests to drivers, tend to maximize profit for the system and/or minimize waiting time for riders. Such platforms can exacerbate biases that drivers may have over certain types of requests.
Dickerson, J. +4 more
core +2 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Profit Sharing and Investment by Regulated Utilities: a Welfare Analysis [PDF]
We analyse the effects of different regulatory schemes (price cap and profit sharing) on a firm’s investment of endogenous size. Using a real option approach in continuous time, we show that profit sharing does not delay a firm’s start-up investment ...
Carlo Scarpa +2 more
core
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source