Results 191 to 200 of about 24,050 (247)

Association of Neurodevelopmental Disorders and Congenital Anomalies With Prenatal Multiple Sclerosis Treatment—Real‐World Historical Cohort Study

Clinical Pharmacology &Therapeutics, EarlyView.
There is a paucity of data regarding the effects of prenatal disease‐modifying therapies (DMTs) for multiple sclerosis (MS), on congenital anomalies in the offspring. Moreover, data on the association with neurodevelopmental disorders are lacking. This is an historical cohort study, within the Israeli Clalit Health Services database (2005–2024) that ...
Bar Rosh, Ofek Levi, Nili Stein, Amir Yahav, Naomi Gronich   +4 more
wiley   +1 more source

Stationary-phase <i>Pseudomonas aeruginosa</i> fluoroquinolone persisters mostly avoid DNA double-stranded breaks. [PDF]

mSphere
Hare PJ, González JR, Mok WWK.
europepmc   +1 more source

Pss knockdown in the midgut causes growth retardation in Drosophila similar to that in human LMHD

Developmental Dynamics, EarlyView.
Abstract Background Phosphatidylserine synthase (PSS), localized in the mitochondrial membrane, synthesizes phosphatidylserine. In humans, mutations in Pss lead to Lenz–Majewski hyperostotic dwarfism, a disorder affecting growth and development. The effects of Pss mutations on the growth of Drosophila melanogaster are not fully known. Hence, this study
Kwan‐Young Kim, You‐Lim Hwang, Sunwoo Yeom, Seung‐Hae Kwon, Sang‐Hak Jeon   +4 more
wiley   +1 more source

Human TET2-Mutant Clonal Hematopoiesis Expansion Is Driven by Distinct Inflammatory Signaling Responses in Stem Cells Versus Myeloid Progeny. [PDF]

Blood Cancer Discov
Huerga Encabo H, D'Agostino G, Sturgess K, Lord AE, Jong ED, Ferrelli A, Sharma A, Mian SA, Habel K, Llorian-Sopena M, Ramesh AP, Mohamad Nor F, Foissner H, Garcia-Albornoz M, Graver L, Papazoglou D, Ngo S, Anjos-Afonso F, Ariza-McNaughton L, Ficz G, Bonnet D.   +20 more
europepmc   +1 more source

Combinatorial expression of glial transcription factors induces Schwann cell‐specific gene expression in mouse embryonic fibroblasts

Developmental Dynamics, EarlyView.
Abstract Background Schwann cells provide peripheral nerve trophic support, myelinate axons, and assist in repair. However, Schwann cell repair capacity is limited by chronic injury, disease, and aging. Schwann cell reprogramming is a cellular conversion strategy that could provide a renewable cell supply to repair injured nerves.
Lauren Belfiore, Anjali Balakrishnan, Yacine Touahri, Dawn Zinyk, Humna Noman, Satoshi Okawa, Jeff Biernaskie, Carol Schuurmans   +7 more
wiley   +1 more source

A nuclear-encoded endonuclease governs the paternal transmission of mitochondria in Cucumis plants. [PDF]

Nat Commun
Shen J, Lyu X, Xu X, Wang Z, Zhang Y, Wang C, Munaiz ED, Zhang M, Havey MJ, Shou W.   +9 more
europepmc   +1 more source

Heterozygous Med13l mice recapitulate a developmental growth delay and craniofacial anomalies seen in MED13L syndrome

Developmental Dynamics, EarlyView.
Abstract Background Gene transcription is crucial for embryo and postnatal development and is regulated by the Mediator complex. Mediator is comprised of four submodules, including the kinase submodule (CKM). The CKM consists of MED13, MED12, CDK8, and CCNC.
Anna K. Leinheiser, Timothy T. Nguyen, Kayla M. Henry, Mariela Rosales, Eric Van Otterloo, Chad E. Grueter   +5 more
wiley   +1 more source

The chromosome-level genome of Hemerocallis middendorffii provides new insights into the floral scents and color biosynthesis in Chinese native daylily. [PDF]

BMC Plant Biol
Sun M, Han B, Xiao J, Yu H, Jia Y, Yuan S, Yao J, Xing Q, Wu D, Sun G, Zhang J.   +10 more
europepmc   +1 more source

Morphological and molecular evidence supporting advantages of apomictic seed production in castor bean (Ricinus communis L.). [PDF]

BMC Plant Biol
Setayeshnasab M, Sabzalian MR, Rahimmalek M, Lohrasebi T.   +3 more
europepmc   +1 more source