Results 131 to 140 of about 569,127 (341)

Translation From Mice to Men: Are Dogs a Dodgy Intermediate? [PDF]

European Medical Journal Hepatology, 2014
Alternatives for liver transplantation in severe liver disease are urgently needed in view of the limited availability of donor livers. The use of embryonic stem cells (ES) or hepatic progenitor cells (HPC) has been investigated in mice models of acute ...
Hedwig S. Kruitwagen, Bart Spee, Hille Fieten, Frank G. van Steenbeek, Baukje A. Schotanus, Louis C. Penning   +5 more
doaj  

Mathematical modeling supports substantial mouse neural progenitor cell death

Neural Development, 2009
Background Existing quantitative models of mouse cerebral cortical development are not fully constrained by experimental data. Results Here, we use simple difference equations to model neural progenitor cell fate decisions, incorporating intermediate ...
MacMillan Hugh R, McConnell Michael J, Chun Jerold   +2 more
doaj   +1 more source

Separation of blast cell and T-lymphocyte progenitors in the blood of patients with acute myeloblastic leukemia [PDF]

, 1979
MD Minden, RN Buick, E. A. McCulloch
openalex   +1 more source

Mechanically and Chemically Defined PEG Hydrogels Improve Reproducibility in Human Cardioid Development

Advanced Healthcare Materials, EarlyView.
Synthetic matrix metalloproteinase (MMP)‐degradable polyethylene glycol (PEG)‐based hydrogels are developed to investigate the influence of mechanical and biochemical cues on cardioid development. Matrix stiffness and cell adhesion motifs significantly regulate cardioid formation, chamber morphogenesis, contractile function, and cardioid transcriptome.
Yuanhui Song, Michael Seitz, Andrew Kowalczewski, Nhu Y Mai, Era Jain, Huaxiao Yang, Zhen Ma   +6 more
wiley   +1 more source

Engineering Assembloids to Mimic Graft‐Host Skeletal Muscle Interaction

Advanced Healthcare Materials, EarlyView.
This study develops a graft‐host skeletal muscle assembloid model combining neuromuscular organoids with tissue‐engineered constructs. Pre‐seeding decellularized muscles with myogenic cells enhances cell migration and axon invasion from the organoid. The model exhibits regenerative capacity following acute damage, advancing the understanding of human ...
Lucia Rossi, Beatrice Auletta, Luigi Sartore, Marco La Placa, Giada Cecconi, Pietro Chiolerio, Edoardo Maghin, Silvia Angiolillo, Eugenia Carraro, Onelia Gagliano, Cecilia Laterza, Nicola Elvassore, Martina Piccoli, Anna Urciuolo   +13 more
wiley   +1 more source

Flow Cytometric Determination of Circulating Progenitor Cells in Patients With Pulmonary Arterial Hypertension: A Systematic Review

Pulmonary Circulation
Pulmonary arterial hypertension (PAH) is characterized by progressive narrowing and obliteration of distal, pre‐capillary pulmonary vessels. Yet, noninvasive biomarkers that reflect this disease‐defining process are lacking.
Kimia Heydari, Carrie Johnson, I. Diane Cooper, Kadija Hersi, Carl Tanba, Junfeng Sun, Michael A. Solomon, Jason M. Elinoff   +7 more
doaj   +1 more source

The integrin α9β1 on hematopoietic stem and progenitor cells: involvement in cell adhesion, proliferation and differentiation

Haematologica, 2009
Background Hematopoietic stem and progenitor cells can interact with their microenvironment via integrins which are adhesion receptors consisting of α and β subunits.
Thomas D. Schreiber, Carolin Steinl, Mike Essl, Harald Abele, Konstanze Geiger, Claudia A. Müller, Wilhelm K. Aicher, Gerd Klein   +7 more
doaj   +1 more source

Engineering the Future of Restorative Clinical Peripheral Nerve Surgery

Advanced Healthcare Materials, EarlyView.
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell, Zarina S. Ali, Eric L. Zager, Joseph M. Rosen, Mykhailo M. Tatarchuk, D. Kacy Cullen   +5 more
wiley   +1 more source

GRANULOPOIESIS IN THE HUMAN EMBRYONIC LIVER: DETECTION OF GRANULOCYTIC PROGENITOR CELLS BY IN VITRO METHODS [PDF]

, 1978
Yoram Barak, Yocheved Karov, M Lancet, Stanley Levin   +3 more
openalex   +1 more source

Glucocorticoids Alter Bone Microvascular Barrier via MAPK/Connexin43 Mechanisms

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Osteoporosis induced by Glucocorticoids (GCs) is a common complication of long‐term GC use in patients with inflammatory and autoimmune conditions, often leading to an increased fracture risk. A 3D bicellular endo‐osteo microfluidic platform is developed to explore pathogenic mechanisms underlying GCs‐induced osteoporosis, highlighting a novel MAPK ...
Eun‐Jin Lee, Peter Lialios, Micaila Curtis, James Williams IV, Yoontae Kim, Paul Salipante, Steven Hudson, Mandy B. Esch, Moshe Levi, Joanna Kitlinska, Stella Alimperti   +10 more
wiley   +1 more source