Engineering Complexity: Advances in 3D Breast Cancer Models for Precision Oncology
In vitro breast cancer models that closely mimic the complex biological and cellular interactions within the tumor microenvironment hold strong promise for enhancing our understanding of tumor progression, immune system behavior, and resistance to therapies, which are essential for developing personalized cancer treatments. Abstract Engineered in vitro
Wonwoo Jeong, Sang Jin Lee
wiley +1 more source
Prostaglandin E1 restores endothelial progenitor cell function in systemic sclerosis. [PDF]
Potjewijd J+5 more
europepmc +1 more source
Microphysiological Systems of Lymphatics and Immune Organs
This review surveys recent progress in engineering lymphatic microenvironments and immune organoids within microphysiological systems, emphasizing innovative strategies to recreate the biochemical and biophysical complexity of native lymphatic tissues.
Ishita Jain+2 more
wiley +1 more source
An analysis of the multilineage production of human hematopoietic progenitors in long-term bone marrow culture: evidence that reactive oxygen intermediates derived from mature phagocytic cells have a role in limiting progenitor cell self-renewal [PDF]
RC Meagher, AJ Salvado, DG Wright
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Progressive Insights into 3D Bioprinting for Corneal Tissue Restoration
This review explores the potential of 3D bioprinting to replicate the complex structure and function of the human cornea. It highlights key advances in bioink development, printing modalities, and in vivo performance, while addressing current challenges and emerging strategies. The review emphasizes bioprinting's promise to overcome donor shortages and
Ilayda Namli+6 more
wiley +1 more source
Connexin 41.8 governs timely haematopoietic stem and progenitor cell specification. [PDF]
Petzold T+5 more
europepmc +1 more source
The effect of prostaglandins E1 and E2 on macrophage progenitor cells with high proliferative potential in mouse bone marrow in vitro [PDF]
AB Kriegler, TR Bradley, GS Hodgson
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Adipocyte membrane‐coated nanoparticles loaded with rosiglitazone in hydrogel offer an alternative approach to conventional obesity treatments. This system selectively targets adipocytes, inducing lipolysis by activating chaperone‐mediated autophagy through mild photothermal stimulation.
Jaehyun Choi+8 more
wiley +1 more source
Post-thaw dimethyl sulfoxide reduction in autologous peripheral blood progenitor cell suspensions. [PDF]
Jandová M+6 more
europepmc +1 more source
Dendrimers Improve Apolipoprotein Nanoparticle mRNA Delivery to Immune Cells
Apolipoprotein nanoparticle (aNP) platform technology efficiently delivers RNA to immune cells following systemic administration. Here, it is demonstrated that incorporating polyvalent ionizable cationic dendrimers in aNPs enables robust mRNA complexation and functional delivery.
Mirre M. Trines+24 more
wiley +1 more source