Results 211 to 220 of about 597,496 (364)

Dendrimers Improve Apolipoprotein Nanoparticle mRNA Delivery to Immune Cells

Advanced Materials, EarlyView.
Apolipoprotein nanoparticle (aNP) platform technology efficiently delivers RNA to immune cells following systemic administration. Here, it is demonstrated that incorporating polyvalent ionizable cationic dendrimers in aNPs enables robust mRNA complexation and functional delivery.
Mirre M. Trines, Daniek Hoorn, Stijn R.J. Hofstraat, Robby C. Zwolsman, Tom Anbergen, Iris Versteeg, Yuri van Elsas, Jeroen Deckers, Merel M.A. Hendrikx, Teun Kleuskens, Youssef B. Darwish, Gijs W.B. Ros, Sjoerd F. Dijkstra, Bram Priem, Matt Timmers, P. Michel Fransen, Maarten J. Pouderoijen, Bas F.M. de Waal, E.W. Meijer, Thijs J. Beldman, Yohana C. Toner, Ewelina Kluza, Willem J.M. Mulder, Henk M. Janssen, Roy van der Meel   +24 more
wiley   +1 more source

Advancing Intervertebral Disc Biology via Omics: Implications for Nucleus Pulposus Progenitor Cell-Based Regeneration. [PDF]

JOR Spine
Stirnimann A, Schlagenhof L, Gantenbein B, Ille F.   +3 more
europepmc   +1 more source

The Space Within: How Architected Voids Promote Tissue Formation

Advanced Materials, EarlyView.
This review explores the role of void spaces in tissue engineering scaffolds and examines four key methods for introducing porosity into hydrogels at different scales. It discusses sacrificial templating, microgels, phase separation, and 3D printing, highlighting principles, advantages, and limitations. It also addresses emerging strategies integrating
Anna Puiggalí‐Jou, Isabel B. Hui, Carla Fernandez‐Rico, Marcy Zenobi‐Wong   +3 more
wiley   +1 more source

Murine hematopoietic progenitor cell lines with erythroid and megakaryocyte potential. [PDF]

Nat Commun
Wu R, Salehi F, Redecke V, Ma Z, Marchetti M, Finkelstein D, Xu P, Cheng Y, Queisser KA, Petrey AC, Field CO, Ahn HS, Poncz M, Weiss MJ, Häcker H.   +14 more
europepmc   +1 more source

Sacrificial Biofabrication for Vascularization: Concept, Materials, Technologies, and Applications

Advanced Materials, EarlyView.
Vasculature is indispensable for tissue viability in regenerative medicine. The sacrificial biofabrication enables precise fabrication of vascular channels by using temporary templates that are subsequently removed. This review defines the concept and delves into sacrificial materials, surrounding materials, fabrication technologies, and biomedical ...
Jiezhong Shi, Chunyao Wang, Xuan Mei, Ben Zhang, Junxi Wu, Rylie A. Green, Yu Shrike Zhang, Wenmiao Shu   +7 more
wiley   +1 more source

Remodeling of calcium signaling and store operated calcium entry as a consequence of human neural progenitor cell differentiation. [PDF]

Sci Rep
Chalmers SB, Robitaille M, Sadras F, Roberts-Thomson SJ, Monteith GR.   +4 more
europepmc   +1 more source

Nanostructured Protein Surfaces Inspired by Spider Silk

Advanced Materials, EarlyView.
Harnessing recombinant spider silk technology, bioengineered spidroin variants enable the creation of functionalized nanostructured coatings with tunable affinity for specific targets, supporting a broad range of applications ‐ from antifouling surfaces and targeted drug delivery to advanced cell therapies and precision bio‐patterning via lithography ...
Martin Humenik, Thomas Scheibel
wiley   +1 more source

Transcriptome and chromatin accessibility divergence during differentiation of a bipotential progenitor cell population to erythroblasts and megakaryocytes. [PDF]

J Biol Chem
Mishra T, Giardine BM, Morrissey CS, Keller CA, Heuston EF, Anderson SM, Paralkar VR, Pimkin M, Weiss MJ, Bodine DM, Hardison RC.   +10 more
europepmc   +1 more source

Myelin protein zero (P0)- and Wnt1-Cre marked muscle resident neural crest-derived mesenchymal progenitor cells give rise to heterotopic ossification in mouse models

, 2022
Chengzhu Zhao, Yoshiko Inada, Kazuya Sekiguchi, Kyosuke Hino, Megumi Nishio, Yasuhiro Yamada, Shuichi Matsuda, Junya Toguchida, Makoto Ikeya   +8 more
openalex   +1 more source

The Bionic Interface: Considering the Material Mediated Electrical Stimulation of Stem Cells

Advanced Materials, EarlyView.
Electrical stimulation directs stem cell fate in tissue engineering. Cellular responses are influenced by membrane properties, intrinsic cell state, material charge‐transport characteristics, and the applied electrical signal. Additionally, a material’s ability to inject, store, and redistribute charge further modulates these responses.
Kaiwen Zhang, Daniel De Maria, Mercyjayapriya Jebakumar, James Collins, Kate E. Fox, Peter C. Sherrell, Amy Gelmi   +6 more
wiley   +1 more source