Results 211 to 220 of about 340,012 (316)

The mechanisms and applications of endothelial progenitor cell therapy in the treatment of intracranial aneurysm. [PDF]

J Transl Med
Shen S, Pan T, Liu P, Tian Y, Shi Y, Zhu W.   +5 more
europepmc   +1 more source

Integrative Omics Reveals Glutamine Catabolism‐Driven Apoptotic Suppression in Monocytes upon Mechanical Unloading

Advanced Science, EarlyView.
This research integrated multi‐omics analysis of bone tissue from HLU and control mice revealed that mechanical unloading suppresses intrinsic apoptosis and augments glutamine (Gln) catabolism in osteoclast lineage cells. The findings highlight pivotal roles for SLC1A5‐mediated Gln metabolism and XIAP/Diablo axis‐mediated apoptosis suppression.
Yi Ding, Fan Tong, Mingqiu Liu, Pin Yang, Jing Zeng, Yinghua Wei, Chunlin Li, Dong Li, Cheng Chang, Yangjun Zhang, Shaoqiong Yi, Fan Hu, Wenjie Shu, Lingqiang Zhang, Chun‐Ping Cui   +14 more
wiley   +1 more source

Corrigendum to "Repurposing Treprostinil for Enhancing Hematopoietic Progenitor Cell Transplantation". [PDF]

Mol Pharmacol
europepmc   +1 more source

A spatiotemporal cell atlas of cardiopulmonary progenitor cell allocation during development. [PDF]

Cell Rep
Wen H, Chandrasekaran P, Jin A, Pankin J, Lu M, Liberti DC, Zepp JA, Jain R, Morrisey EE, Michki SN, Frank DB.   +10 more
europepmc   +1 more source

Life Factors and Melanoma: From the Macroscopic State to the Molecular Mechanism

Advanced Science, EarlyView.
Melanoma, an aggressive skin cancer, arises from dynamic interactions between genetic, environmental, and lifestyle factors. This review explores how age, gender, obesity, diet, exercise, smoking, alcohol, UV exposure, circadian rhythms, and medications influence melanoma risk and progression.
Hanbin Wang, Hengxiang Zhang, Yuqi Zhou, Chunying Li, Weinan Guo   +4 more
wiley   +1 more source

Emerging role of neural stem/progenitor cell secretome in brain inflammatory response modulation. [PDF]

Pharmacol Rep
Łukowicz K, Grygier B, Basta-Kaim A.
europepmc   +1 more source

Developmental Hypoxia Enhances Kidney Organoid Complexity and Maturity

Advanced Science, EarlyView.
The current bottleneck in metanephric mesenchyme (MM)‐derived nephron organoid development is the absence of a connected network of collecting ducts (CD) derived from the ureteric bud (UB). To address this limitation, this study proposes a hypoxia‐based differentiation method that mimics the natural renal developmental environment, enabling the ...
Hyeonji Lim, Dohui Kim, Haejin Yoon, Joo H. Kang, Yong Jun Kim, Dong Sung Kim, Tae‐Eun Park   +6 more
wiley   +1 more source

The m5C reader Ybx1 regulates embryonic cortical neurogenesis by promoting progenitor cell cycle progression. [PDF]

PLoS Biol
Zhang J, Che P, Yang Z, Zhang P, Shui Y, Lu X, Xu J, She Y, Zhang Y, Yu J, Ji SJ.   +10 more
europepmc   +1 more source

RECOVERY OF HEMOPOIETIC STROMAL PROGENITOR CELLS AFTER LETHAL TOTAL-BODY IRRADIATION AND BONE MARROW TRANSPLANTATION IN MICE

, 1985
Aldert H. Piersma, Kelvin G.M. Brockbank, Rob E. Ploemacher, Cecile P. E. Ottenheim   +3 more
openalex   +1 more source

Single‐Cell Transcriptome Analysis Reveals That Hmga2 Regulates Neuroinflammation and Retinal Function by Modulating Müller Cell Autophagy Through PI3K/AKT Signaling Following MCAO‐Induced Retinal Ischemia

Advanced Science, EarlyView.
Employing snRNA‐seq post‐MCAO‐induced retinal ischemia (RI), this study revealed a novel Hmga2‐high Müller cell subpopulation. Hmga2 knockout alleviated neuroinflammation and RI symptoms, potentially by binding PI3K and regulating Müller cell autophagy.
Weihao Lv, Juzheng Yuan, Zhe Ruan, Ya‐nan Dou, Hongchen Zhang, Xiaowei Fei, Leiying Chen, Zehan Zhang, Kai Yang, Xiuquan Wu, Zhou Fei, Fei Fei   +11 more
wiley   +1 more source