This study establishes a robust and reproducible protocol for generating human otic neuronal spheroids (hONS) from cryopreserved hPSC‐derived pre‐placodal ectoderm cells. These hONS further differentiate into functional SGN‐like neurons, which extend neurite projections toward both murine hair cells and human cortical organoids, thereby forming ...
Gaoying Sun +15 more
wiley +1 more source
Transcriptome and chromatin accessibility divergence during differentiation of a bipotential progenitor cell population to erythroblasts and megakaryocytes. [PDF]
Mishra T +10 more
europepmc +1 more source
Links between hepatic fibrosis, ductular reaction, and progenitor cell expansion.
Michael J. Williams +2 more
semanticscholar +1 more source
NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang +18 more
wiley +1 more source
The citrullinating enzyme PADI4 governs progenitor cell proliferation and translation in developing hair follicles. [PDF]
Patil KV +11 more
europepmc +1 more source
Pentose phosphate pathway activity regulates TCF1+ progenitor CD8+ T cells to improve immunotherapy 4810 [PDF]
Geoffrey J. Markowitz +2 more
openalex +1 more source
Chromatin Topology Reconfiguration Orchestrates Thermotolerant Male Fertility via GhAL5 in Cotton
This study investigates cotton’s high‐temperature (HT) response using multi‑omics. Dynamic 3D genome changes drive expression bias affecting male fertility. The tolerant line shows controlled chromatin dynamics, while the sensitive line exhibits overactivation.
Yanlong Li +15 more
wiley +1 more source
Interleukin 10 enhances endothelial progenitor cell-mediated angiogenesis in extrahepatic portal venous obstruction. [PDF]
Zhang JS.
europepmc +1 more source
Thymus-repopulating stem and progenitor cells in mouse bone marrow
Walentina A. T. Slieker
openalex +1 more source

