Results 221 to 230 of about 11,013,611 (366)

Cryopreserved Human Otic Neuronal Spheroids Self‐assemble for Functional Connectivity Analysis and Long‐term Ototoxicity Evaluation

open access: yesAdvanced Science, EarlyView.
This study establishes a robust and reproducible protocol for generating human otic neuronal spheroids (hONS) from cryopreserved hPSC‐derived pre‐placodal ectoderm cells. These hONS further differentiate into functional SGN‐like neurons, which extend neurite projections toward both murine hair cells and human cortical organoids, thereby forming ...
Gaoying Sun   +15 more
wiley   +1 more source

Transcriptome and chromatin accessibility divergence during differentiation of a bipotential progenitor cell population to erythroblasts and megakaryocytes. [PDF]

open access: yesJ Biol Chem
Mishra T   +10 more
europepmc   +1 more source

Links between hepatic fibrosis, ductular reaction, and progenitor cell expansion.

open access: yesGastroenterology, 2014
Michael J. Williams   +2 more
semanticscholar   +1 more source

NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang   +18 more
wiley   +1 more source

The citrullinating enzyme PADI4 governs progenitor cell proliferation and translation in developing hair follicles. [PDF]

open access: yesSci Adv
Patil KV   +11 more
europepmc   +1 more source

Chromatin Topology Reconfiguration Orchestrates Thermotolerant Male Fertility via GhAL5 in Cotton

open access: yesAdvanced Science, EarlyView.
This study investigates cotton’s high‐temperature (HT) response using multi‑omics. Dynamic 3D genome changes drive expression bias affecting male fertility. The tolerant line shows controlled chromatin dynamics, while the sensitive line exhibits overactivation.
Yanlong Li   +15 more
wiley   +1 more source

Hippo pathway effectors control cardiac progenitor cell fate by acting as dynamic sensors of substrate mechanics and nanostructure.

open access: yesACS Nano, 2014
Diogo Mosqueira   +14 more
semanticscholar   +1 more source

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