Results 241 to 250 of about 11,013,611 (366)

A Patient‐Derived Organ‐on‐Chip Platform for Modeling the Tumor Microenvironment and Drug Responses in Pancreatic Cancer

Advanced Science, EarlyView.
Researchers have developed a patient‐derived organ‐on‐a‐chip model for pancreatic cancer by integrating cancer cells with supportive stromal and immune cells inside a microfluidic device. This system mimics the tumor microenvironment, enabling personalized testing of chemotherapy and immunotherapy, and offering new insights into how targeting ...
Darbaz Adnan, Natan Roberto de Barros, Luca S. Santovito, Xuhong Cheng, Kristi M. Lawrence, Mariah K. Barnett, Martine D. Boetto, Neal Mehta, Ajaypal Singh, Lin Cheng, Xiangsheng Huang, Faraz Bishehsari   +11 more
wiley   +1 more source

Prostaglandin E1 restores endothelial progenitor cell function in systemic sclerosis. [PDF]

Rheumatology (Oxford)
Potjewijd J, Tobal R, Arends SJ, Debrus-Palmans L, Damoiseaux JGMC, van Paassen P.   +5 more
europepmc   +1 more source

Role of bone morphogenetic protein 2 in the crosstalk between endothelial progenitor cells and mesenchymal stem cells

, 2006
Martin Kristian Raida, Anthony Heymann, Christian Günther, D Niederwieser   +3 more
openalex   +2 more sources

Osteopontin neutralisation abrogates the liver progenitor cell response and fibrogenesis in mice

Gut, 2014
J. Coombes, M. Swiderska-syn, Laurent Dollé, D. Reid, B. Eksteen, L. Claridge, M. Briones‐Orta, S. Shetty, Y. Oo, A. Riva, S. Chokshi, S. Papa, Z. Mi, P. Kuo, Roger Williams, A. Canbay, David John Adams, A. Diehl, L. V. Grunsven, Steve S. Choi, Steve S. Choi, Wing Syn, Wing Syn, Wing Syn   +23 more
semanticscholar   +1 more source

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

Advanced Science, EarlyView.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu, Anwen Yin, Xiang Yu, Mingxin Wang, Jiahui Zhang, Kerong Liu, Yutong Hou, Minkai Cao, Yiting Zhang, Xiaoxiao Zhang, Yao Gao, Xirong Guo, Le Zhang, Yun Li   +13 more
wiley   +1 more source

A Multipotent PROX1+ Tumor Stem/Progenitor Cell Population Emerges during Intestinal Tumorigenesis and Mediates Radioresistance in Colorectal Cancer. [PDF]

Cancer Res
Kallio P, Bessone C, Seyednasrollah F, Brodkin J, Lassila M, Högström J, González-Loyola A, Petrova TV, Haglund C, Alitalo K.   +9 more
europepmc   +1 more source

Reintroduction of C/EBPα in leukemic CD34+ stem/progenitor cells impairs self-renewal and partially restores myelopoiesis

, 2007
Hein Schepers, Albertus T.J. Wierenga, Djoke van Gosliga, Bart J. L. Eggen, Edo Vellenga, Jan Jacob Schuringa   +5 more
openalex   +2 more sources

Nurr1 Orchestrates Claustrum Development and Functionality

Advanced Science, EarlyView.
Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan, Andrew G. Newman, Pauline Lange, Susanne Müller, Marco Foddis, Stefan Paul Koch, Philipp Böhm‐Sturm, Maron Mantwill, Carsten Finke, Penghui Deng, Melissa Long, Dietmar Schmitz, Victor Tarabykin   +12 more
wiley   +1 more source

Effect of 2D and 3D ECM and Biomechanical Cues on Human iPSC-Derived Liver Progenitor Cell Differentiation. [PDF]

Adv Healthc Mater
Jain I, Grenci B, Ryoo H, Yuan Y, Khetani SR, Underhill GH.   +5 more
europepmc   +1 more source

The CD133+ Stem/Progenitor-Like Cell Subset Is Increased in Human Milk and Peripheral Blood of HIV-Positive Women

, 2020
Jacqueline María Valverde-Villegas, Mar Naranjo‐Gómez, Mélusine Durand, David Rutagwera, Anne‐Sophie Bedin, Chipepo Kankasa, Ségolène Debiesse, Nicolas Nagot, Édouard Tuaillon, Philippe Van de Perre, Jean‐Pierre Molès   +10 more
openalex   +1 more source