The impact of extracellular matrix proteins on bovine fibro-adipogenic progenitor cell adhesion, proliferation, and differentiation in vitro. [PDF]
Gish P+5 more
europepmc +1 more source
Drought is a major cause of crop losses across agricultural regions. Rhizosheath formation enhances plant resistance to drought. Polyploids may tolerate stress more effectively through increased interactions with bacteria. However, the contributions of tetraploid rice associated microbiota to rhizosheath formation under soil drying remain unclear ...
Feiyun Xu+23 more
wiley +1 more source
Neural progenitor cell-derived exosomes in ischemia/reperfusion injury in cardiomyoblasts. [PDF]
Arvola O+3 more
europepmc +1 more source
A gastrula‐premarked enhancer within the first intron of Cdx2 governs posterior embryonic development via both regulating Cdx2 expression in cis and coordinating TGF‐β signaling in trans to ensure proper posterior body development. Functional rescue in gastruloids reveals a Cdx2‐independent pathway, highlighting p‐Enh‐eRNA as key epigenetic ...
Yingying Chen+16 more
wiley +1 more source
Trimethylamine-N-Oxide Impedes Late Endothelial Progenitor Cell-Mediated Revascularization by Triggering Mitochondrial Apoptosis via Suppression of MnSOD. [PDF]
Shao Y+7 more
europepmc +1 more source
Single‐Cell RNA Sequencing Delineates Renal Anti‐Fibrotic Mechanisms Mediated by TRPC6 Inhibition
Single‐cell transcriptomics reveals how TRPC6 inhibition alters renal cell composition and gene expression in CKD. The study uncovers a novel endothelial subpopulation (ECRIN), highlights key inflammatory and fibrotic pathways, and identifies a Prnp‐driven network linked to fibrosis resolution, offering mechanistic insight into TRPC6 as a potential ...
Yao Xu+12 more
wiley +1 more source
LRP5 promotes adipose progenitor cell fitness and adipocyte insulin sensitivity. [PDF]
Loh NY+14 more
europepmc +1 more source
Human Nervous System‐Based Biohybrid Robot‐On‐A‐Chip with Sensing Function for Toxicity Screening
Human nervous system‐based biohybrid robot‐on‐a chip with eye function as sensing system in addition to brain/motor neuron/muscle functions is proposed. Upon light stimulation, the eye assembloid generates electrophysiological signals, which are transmitted through the cerebral organoid and motor neuron spheroid, inducing muscle movement.
Minkyu Shin+6 more
wiley +1 more source
Colony formation by primitive hemopoietic progenitor cells in serum-free medium.
James F. Eliason, N Odartchenko
openalex +1 more source
This study uncovers STAT6‐driven pulmonary fibrosis (PF) via suppression of PRKN‐mediated airway epithelial mitophagy, triggering mitochondrial dysfunction and ferroptosis. Rifabutin is identified as a potent STAT6 inhibitor that effectively reverses fibrotic progression. These findings reveal the STAT6‐PRKN axis as a pathogenic regulator and provide a
Youjing Yang+7 more
wiley +1 more source