Results 271 to 280 of about 11,013,611 (366)

Alpha-ketoglutarate rescues impaired endothelial progenitor cell-mediated angiogenesis in diabetic mice. [PDF]

open access: yesFront Pharmacol
Qiu JH   +7 more
europepmc   +1 more source

Safety of a Medicinal Product Based on Human Glial Progenitor Cells: A Pilot Study of Retrobulbar Administration in C57BL/6J Mice

open access: diamond
В. О. Небогатиков   +7 more
openalex   +1 more source

CD168 Identifies Proliferating Pancreatic Islet Cells in Murine and Human

open access: yesAdvanced Science, EarlyView.
This study identifies CD168 as a conserved surface marker for proliferating β‐cells in mouse, human islets, and pancreatic islet tumors. CD168⁺ cells show high proliferation and low insulin expression. CD168+ cells form mostly uni‐β lineage clones, and some of the clones are multi‐lineage.
Shubo Yuan   +21 more
wiley   +1 more source

A vast stem-progenitor cell pool, richly vascular system, and hybrid ossification drive the daily centimeter-scale elongation of bony antlers. [PDF]

open access: yesImeta
Ba H   +22 more
europepmc   +1 more source

CD45-Directed Radioimmunotherapy with the Alpha-Emitter Astatine-211 As Conditioning for Autologous Hematopoietic Stem/Progenitor Cell Gene Therapy: Results from a Nonhuman Primate Model [PDF]

open access: bronze
Stefan Radtke   +10 more
openalex   +1 more source

Type I Interferon Pathway Activation Disrupts Monocyte Maturation and Enhances Immune Evasion in Multiple Myeloma

open access: yesAdvanced Science, EarlyView.
This study shows that monocytes in multiple myeloma display an excessive interferon response, leading to transcriptional reprogramming and altered differentiation. Using single‐cell sequencing, coculture experiments, and patient samples before and after therapy, the authors demonstrate that induction treatment reduces this interferon response ...
Jian Cui   +18 more
wiley   +1 more source

Regulation of feather length: FGF/IGF signaling and NOTCH/YAP modulation of progenitor cell topology. [PDF]

open access: yesSci Adv
Wu P   +14 more
europepmc   +1 more source

RUNX2 Activation in Fibro/Adipogenic Progenitors Promotes Muscle Fibrosis in Muscular Dystrophy

open access: yesAdvanced Science, EarlyView.
This study revealed a novel role of the chemokine‐TGF‐β1‐RUNX2 axis in determining the fate of FAP differentiation and modulating muscle fibrosis in patients and mice with muscular dystrophies. ABSTRACT Clinical evidence indicates concurrent muscle inflammation and fibrosis in muscular dystrophies (MDs); however, the molecular mechanisms underlying ...
Pengkai Wu   +12 more
wiley   +1 more source

Postoperative Stress Accelerates Atherosclerosis Through Inflammatory Remodeling of the HDL Proteome and Impaired Reverse Cholesterol Transport

open access: yesAdvanced Science, EarlyView.
The study shows that noncardiac surgical inflammation rapidly disrupts HDL function and cholesterol efflux in mice and human patients. Impaired reverse cholesterol transport after surgery drives rapid lipid accumulation, NETosis, and apoptosis within atherosclerotic plaques.
Dominique M. Boucher   +15 more
wiley   +1 more source

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