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Pancreatic Cells and Their Progenitors
2006Both type 1 and type 2 diabetes patients would greatly benefit from transplantation of insulin-producing pancreatic beta cells; however, a severe shortage of transplantable beta cells is a major current limitation in the use of such therapy. Understanding the mechanisms by which beta cells are naturally formed is therefore a central challenge for ...
Seth J. Salpeter, Yuval Dor
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Gastroenterology Clinics of North America, 2017
Liver regeneration is a fascinating and complex process with many medical implications. An important component of this regenerative process is the hepatic progenitor cell (HPC). These appealing cells are able to participate in the renewal of hepatocytes and cholangiocytes when the normal homeostatic regeneration is exhausted. Moreover, the HPC niche is
Matthias Van Haele, Tania Roskams
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Liver regeneration is a fascinating and complex process with many medical implications. An important component of this regenerative process is the hepatic progenitor cell (HPC). These appealing cells are able to participate in the renewal of hepatocytes and cholangiocytes when the normal homeostatic regeneration is exhausted. Moreover, the HPC niche is
Matthias Van Haele, Tania Roskams
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2013
For years, researchers have searched for ways to replace the insulin-producing beta cells of the pancreas to treat diabetes. Much attention has been paid to the identification of stem/progenitor cells that can be expanded and differentiated towards beta cells in view of obtaining a renewable source for cell transplantation therapy.
Houbracken, Isabelle +2 more
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For years, researchers have searched for ways to replace the insulin-producing beta cells of the pancreas to treat diabetes. Much attention has been paid to the identification of stem/progenitor cells that can be expanded and differentiated towards beta cells in view of obtaining a renewable source for cell transplantation therapy.
Houbracken, Isabelle +2 more
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Exercise and Cardiovascular Progenitor Cells
Comprehensive Physiology, 2019ABSTRACTAutologous stem/progenitor cell‐based methods to restore blood flow and function to ischemic tissues are clinically appealing for the substantial proportion of the population with cardiovascular diseases. Early preclinical and case studies established the therapeutic potential of autologous cell therapies for neovascularization in ischemic ...
James M. Hagberg +8 more
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Characterization of endothelial progenitor cells
Biochemical and Biophysical Research Communications, 2005N ...
FADINI, GIAN PAOLO +2 more
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Autophagy in stem and progenitor cells
Cellular and Molecular Life Sciences, 2015Autophagy is a highly conserved cellular process, responsible for the degradation and recycling of damaged and/or outlived proteins and organelles. This is the major cellular pathway, acting throughout the formation of cytosolic vesicles, called autophagosomes, for the delivering to lysosome.
Rodolfo C +2 more
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Progenitor cell transplantation
Drug and Therapeutics Bulletin, 1997Many leukaemias and solid cancers are now treated with high-dose chemotherapy, an approach made possible by techniques that bolster haematological recovery when bone marrow suppression occurs. The conventional way of reversing marrow suppression has been to give an autologous bone marrow transplant (cells aspirated from the patient's own marrow).
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Vascular Progenitor Cells and Atherosclerosis
Future Cardiology, 2007Vascular regeneration occurs throughout life as a dynamic process. Millions of new endothelial cells are created with essentially the same number of cells undergoing programmed cell death or necrosis every day. As a result, the human vascular tree could be considered to essentially replace its entire endothelial population over a specified number of ...
Adams, B, Xiao, Q, Xu, Q
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Endothelial progenitor cells and preeclampsia
Frontiers in Bioscience, 2007The maternal cardiovascular adaptation to pregnancy involves a complex physiologic response to the presence of the growing conceptus, including alterations in maternal vascular endothelial cells that contribute to a profound fall in total systemic vascular resistance.
Carl A. Hubel +2 more
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Endothelial progenitor cells and thrombosis
Thrombosis Research, 2012The remodelling of existing vessels (i.e. angiogenesis) and the "de novo" vessel formation (i.e. vasculogenesis) occur not only during the embryonic development but also over the entire postnatal life. In 1997, the Asahara group first reported that endothelial progenitor cells circulate in peripheral blood and that they are recruited at sites of ...
Eugenia Rosa Nuzzolo +2 more
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