Results 291 to 300 of about 597,496 (364)

Imaging progenitor cell differentiation during central nervous system remyelination using an MRI gene reporter

Brechbühl EE, Hill MF, Chen CZ, Gaitsch HF, Ros S, Porcu L, Wright AJ, Reich DS, Franklin RJ, Brindle KM.   +9 more
europepmc   +1 more source

An inflammatory T-cell-stromal axis contributes to hematopoietic stem/progenitor cell failure and clonal evolution in human myelodysplastic syndrome. [PDF]

Nat Commun
Chen L, Bian Y, Pronk E, van Dijk C, V D van Tienhoven T, Hoogenboezem RM, Bindels EM, Bosch D, Fazeli S, de Graaf AO, Westers TM, Kholmatov M, Zaugg JB, Moura PL, Hellström-Lindberg E, van de Loosdrecht AA, Jansen JH, Sanders MA, Raaijmakers MHGP.   +18 more
europepmc   +1 more source

In Situ Engineering of Tumor Cells as Self‐Sustaining cDC1 Programming Factories for Effective Cancer Immunotherapy

Advanced Science, EarlyView.
The fused EV platform AS16‐EL@MPLA/p‐FX reprograms tumor cells into cytokine‐producing factories that continuously secrete XCL1 and FLT3L to recruit and differentiate cDC1s, while embedded MPLA activates them through TLR4 signaling and AS16 prevents their exhaustion, thereby enhancing antitumor immunity and establishing durable immune memory against ...
Shuiling Jin, Xiaoxi Wang, Bingyu Li, Xueqin Zhu, Zimai Liu, Jiao Lu, Yuanyuan Wei, Zixian Wu, Kai Li, Tiantian Zhang, Zonghong He, Pingping Zhu, Yuanming Qi, Benyu Liu, Hui Liu, Yongchao Wang, Zhenzhen Chen   +16 more
wiley   +1 more source

Glycolytic flux controls retinal progenitor cell differentiation via regulating Wnt signaling. [PDF]

Elife
Hanna J, Touahri Y, Pak A, Belfiore L, van Oosten E, David LA, Han S, Ilnytskyy Y, Kovalchuk I, Kurrasch D, Okawa S, Del Sol A, Screaton RA, Aubert I, Schuurmans C.   +14 more
europepmc   +1 more source

Microvascular Health as a Key Determinant of Organismal Aging

Advanced Science, EarlyView.
This review spotlights the emerging field of vascular aging, providing a comprehensive and critical overview of the molecular processes and clinical manifestations of vascular dysfunction during aging. By combining basic angioscience concepts with a critical analysis of innovative pre‐clinical aging models and lifestyle interventions, it offers a ...
Mattia Cenciarini, Andrea Uccelli, Francesca Mangili, Myriam Grunewald, Simone Bersini   +4 more
wiley   +1 more source

Rethinking Matrigel: The Complex Journey to Matrix Alternatives in Organoid Culture

Advanced Science, EarlyView.
Matrigel remains the most widely used scaffold in organoid and 3D culture despite its murine origin, variability, and translational limitations. This review discusses the barriers to replacing Matrigel with xeno‐free alternatives and introduces practical tools, including a matrix selection checklist and scaffold assessment criteria, to guide the ...
Lisa Wolff, Sven Hendrix
wiley   +1 more source

The mechanisms and applications of endothelial progenitor cell therapy in the treatment of intracranial aneurysm. [PDF]

J Transl Med
Shen S, Pan T, Liu P, Tian Y, Shi Y, Zhu W.   +5 more
europepmc   +1 more source

Dynamic Fibrous Hydrogels for Stem Cell Homing and In Situ Bone Regeneration

Advanced Science, EarlyView.
A dynamic fibrous hydrogel (DFH) is developed by covalent crosslinking of gelatin with tea‐derived trichomes, which integrates the structural and compositional fidelity of native extracellular matrix with photothermal and oxidative responsiveness, introducing a novel “stem cell recruits stem cell” strategy that orchestrates co‐homing of endogenous and ...
Jianmei Chen, Meiling Su, Xinyu Wu, Hongyu Wu, Haotian Wu, Pinghu Zhang, Xueying An, Zongguang Liu   +7 more
wiley   +1 more source

A spatiotemporal cell atlas of cardiopulmonary progenitor cell allocation during development. [PDF]

Cell Rep
Wen H, Chandrasekaran P, Jin A, Pankin J, Lu M, Liberti DC, Zepp JA, Jain R, Morrisey EE, Michki SN, Frank DB.   +10 more
europepmc   +1 more source

Deciphering cholangiocarcinoma heterogeneity and specific progenitor cell niche of extrahepatic cholangiocarcinoma at single-cell resolution. [PDF]

J Hematol Oncol
Liu C, Wang X, Liu E, Zong Y, Yu W, Jiang Y, Chen J, Gu M, Meng Z, Li J, Liu Y, Zhang Y, Tang J, Wang H, Fu J.   +14 more
europepmc   +1 more source