Results 311 to 320 of about 11,013,611 (366)
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Endothelium, 2006
The identification of circulating endothelial progenitor cells (EPCs) has prompted an explosion of interest in postnatal vasculogenesis and the role of this mechanism in human health and disease. Previously considered restricted to the embryonic phase, the differentiation in situ of progenitor cells to vascular endothelium is now known to occur in the ...
Brendan, Doyle +2 more
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The identification of circulating endothelial progenitor cells (EPCs) has prompted an explosion of interest in postnatal vasculogenesis and the role of this mechanism in human health and disease. Previously considered restricted to the embryonic phase, the differentiation in situ of progenitor cells to vascular endothelium is now known to occur in the ...
Brendan, Doyle +2 more
openaire +2 more sources
Progenitor cell transplantation
Drug and Therapeutics Bulletin, 1997Many leukaemias and solid cancers are now treated with high-dose chemotherapy, an approach made possible by techniques that bolster haematological recovery when bone marrow suppression occurs. The conventional way of reversing marrow suppression has been to give an autologous bone marrow transplant (cells aspirated from the patient's own marrow).
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Stromal Mesenchymal Progenitor Cells
Leukemia & Lymphoma, 1999The precursors of bone, cartilage, fat and muscle cells are likely to be derived from more primitive mesenchymal cells which exhibit some of the characteristics of stem cells. Despite extensive study of stromal cell differentiation, neither mesenchymal stem cells or the more committed, tissue-specific progenitors have been well characterized.
R, Ghilzon, C A, McCulloch, R, Zohar
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Multipotent adult progenitor cells
Best Practice & Research Clinical Haematology, 2011We here discuss the potency and characteristics of various adult derived adherent stem cells with special focus on multipotent adult progenitor cells (MAPC) isolated first in 2002 in our lab. We describe the potency of MAPC, our current understanding in relationship with novel insights gained in epigenetic modifications that increase cellular potency ...
Abhishek, Sohni, Catherine M, Verfaillie
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Resident vascular progenitor cells
Journal of Molecular and Cellular Cardiology, 2011Homeostasis of the vessel wall is essential for maintaining its function, including blood pressure and patency of the lumen. In physiological conditions, the turnover rate of vascular cells, i.e. endothelial and smooth muscle cells, is low, but markedly increased in diseased situations, e.g. vascular injury after angioplasty. It is believed that mature
Torsney, Evelyn, Xu, Qingbo
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Human megakaryocytic progenitor cells
Klinische Wochenschrift, 1987Megakaryocytopoiesis represents one of several differentiation pathways that hematopoietic stem cells may enter. Cells representing intermediate stages of differentiation between pluripotent stem cells and maturing megakaryocytes are called megakaryocytic progenitor cells.
L, Kanz, G W, Löhr, A A, Fauser
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Hematopoietic Progenitor Cell Collection
2012Hematopoietic progenitor cells can be mobilized from the bone marrow microenvironment into the peripheral blood following treatment of patients with myeloid cytokines (GCSF, GMCSF, IL3), a CXCR4 antagonist (Plerixafor) and/or following a hematopoietic recovery from cytotoxic chemotherapy. The hematopoietic stem and progenitor cells are contained within
S Darlene, Marlow, Myra, House
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2013
For years, researchers have searched for ways to replace the insulin-producing beta cells of the pancreas to treat diabetes. Much attention has been paid to the identification of stem/progenitor cells that can be expanded and differentiated towards beta cells in view of obtaining a renewable source for cell transplantation therapy.
Houbracken, Isabelle +2 more
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For years, researchers have searched for ways to replace the insulin-producing beta cells of the pancreas to treat diabetes. Much attention has been paid to the identification of stem/progenitor cells that can be expanded and differentiated towards beta cells in view of obtaining a renewable source for cell transplantation therapy.
Houbracken, Isabelle +2 more
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Vascular Progenitor Cell Mobilization
2012Blood vessel formation plays a key role in both physiologic and pathologic tissue growth and healing. Thus, a thorough understanding of the mechanisms underlying neovascularization will translate into innovative clinical treatment strategies for a wide variety of disease processes.
Kirsten A, Kienstra, Karen K, Hirschi
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Islet-Derived Multipotential Cells/Progenitor Cells
Cell Biochemistry and Biophysics, 2004The pancreatic beta-cell has a pivotal role in the regulation of glucose homeostasis; its death leads to type I diabetes. Neogenesis of beta-cells, the differentiation of beta-cells from non-beta-cells, could be an important mechanism of islet cell repopulation.
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