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Vascular Progenitor Cells and Atherosclerosis
Future Cardiology, 2007Vascular regeneration occurs throughout life as a dynamic process. Millions of new endothelial cells are created with essentially the same number of cells undergoing programmed cell death or necrosis every day. As a result, the human vascular tree could be considered to essentially replace its entire endothelial population over a specified number of ...
Adams, B, Xiao, Q, Xu, Q
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Autophagy in stem and progenitor cells
Cellular and Molecular Life Sciences, 2015Autophagy is a highly conserved cellular process, responsible for the degradation and recycling of damaged and/or outlived proteins and organelles. This is the major cellular pathway, acting throughout the formation of cytosolic vesicles, called autophagosomes, for the delivering to lysosome.
Rodolfo C+2 more
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Progenitor cell transplantation
Drug and Therapeutics Bulletin, 1997Many leukaemias and solid cancers are now treated with high-dose chemotherapy, an approach made possible by techniques that bolster haematological recovery when bone marrow suppression occurs. The conventional way of reversing marrow suppression has been to give an autologous bone marrow transplant (cells aspirated from the patient's own marrow).
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Endothelial progenitor cells and preeclampsia
Frontiers in Bioscience, 2007The maternal cardiovascular adaptation to pregnancy involves a complex physiologic response to the presence of the growing conceptus, including alterations in maternal vascular endothelial cells that contribute to a profound fall in total systemic vascular resistance.
Carl A. Hubel+2 more
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Endothelial progenitor cells and thrombosis
Thrombosis Research, 2012The remodelling of existing vessels (i.e. angiogenesis) and the "de novo" vessel formation (i.e. vasculogenesis) occur not only during the embryonic development but also over the entire postnatal life. In 1997, the Asahara group first reported that endothelial progenitor cells circulate in peripheral blood and that they are recruited at sites of ...
Eugenia Rosa Nuzzolo+2 more
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Expansion of stem and progenitor cells
Current Opinion in Hematology, 1998An increasing interest exists in strategies to manipulate hematopoietic stem cells (HSCs) and hematopoietic progenitor cells (HPCs) in vitro for clinical purposes by use of recombinant hematopoietic growth factors. A major goal of these ex vivo expansion strategies is to expand repopulating HSCs or to generate lineage-committed progenitors in the ...
Lothar Kanz, Benedikt L. Ziegler
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Progenitor cells and retinal angiogenesis
Angiogenesis, 2007Nothing more dramatically captures the imagination of the visually impaired patient or the ophthalmologist treating them than the possibility of rebuilding a damaged retina or vasculature with "stem cells." Stem cells (SC) have been isolated from adult tissues and represent a pool of cells that may serve to facilitate rescue/repair of damaged tissue ...
Mohammad A. El-Kalay+8 more
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Progenitor cells in the adult pancreas
Diabetes/Metabolism Research and Reviews, 2004AbstractThe β‐cell mass in the adult pancreas possesses the ability to undergo limited regeneration following injury. Identifying the progenitor cells involved in this process and understanding the mechanisms leading to their maturation will open new avenues for the treatment of type 1 diabetes.
L. Jorge Góñez+2 more
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Relaxin' with endothelial progenitor cells
Blood, 2012Segal and colleagues in this issue of Blood report their findings about an additional new function for the hormone relaxin: turning on bone marrow–derived endothelial progenitor cells to sites of neoangiogenesis ...
Alice Wang, S. Ananth Karumanchi
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Cytokinetics and regulation of progenitor cells
Journal of Cellular Physiology, 1966Four different assay methods of bone marrow stem cells have been examined with regard to the kinetic pattern following perturbation of the steady-state system, e.g., by irradiation. Basically, the stem cell assays fall into two categories: those depending on grafting hemopoietic cells into suitably treated recipients, and those in which recovery of the
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