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Exercise and Cardiovascular Progenitor Cells
Comprehensive Physiology, 2019ABSTRACTAutologous stem/progenitor cell‐based methods to restore blood flow and function to ischemic tissues are clinically appealing for the substantial proportion of the population with cardiovascular diseases. Early preclinical and case studies established the therapeutic potential of autologous cell therapies for neovascularization in ischemic ...
Rian Q, Landers-Ramos +4 more
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Glia as neural progenitor cells
Trends in Neurosciences, 2003Recent studies have substantially expanded our conception of the roles for glia in function and maintenance of the adult nervous system. Of these reports, several have re-examined the lineage relationships among neural stem cells, their early radial glial derivatives and their mitotically competent neurogenic daughters.
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Hematopoietic Progenitor Cell Collection
2012Hematopoietic progenitor cells can be mobilized from the bone marrow microenvironment into the peripheral blood following treatment of patients with myeloid cytokines (GCSF, GMCSF, IL3), a CXCR4 antagonist (Plerixafor) and/or following a hematopoietic recovery from cytotoxic chemotherapy. The hematopoietic stem and progenitor cells are contained within
S Darlene, Marlow, Myra, House
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Progenitor cells in vascular repair
Current Opinion in Lipidology, 2007A common characteristic of all types of vascular disease is endothelial dysfunction/damage followed by an inflammatory response. Although mature endothelial cells can proliferate and replace damaged cells in the vessel wall, recent findings indicate an impact of stem and progenitor cells in repair process.
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AMPK and Placental Progenitor Cells
2016AMPK is important in numerous physiological systems but plays a vital role in embryonic and placental development. The placenta is a unique organ that is the essential lifeline between the mother and baby during pregnancy and gestation. During placental development, oxygen concentrations are very low until cells differentiate to establish the ...
Melissa R, Kaufman, Thomas L, Brown
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Immortalization of hepatic progenitor cells
Pathologie Biologie, 2004Development of cell therapy-based strategies for the treatment of liver failures and of inherited metabolic diseases has become a necessity because of the limitations of orthotopic liver transplantation, including shortage of donor livers. This shortage limits also the availability for hepatocytes and these terminally differentiated cells cannot be ...
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Progenitor Cells in the Pulmonary Circulation
Proceedings of the American Thoracic Society, 2011The mechanisms involved in the regulation of pulmonary vascular endothelial cells to replace aged or injured cells remains poorly understood, although differences in proliferative potential between the microvascular and macrovascular endothelium are well described.
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The impact of progenitor cells in atherosclerosis
Nature Clinical Practice Cardiovascular Medicine, 2006During the pathogenesis of arteriosclerosis, endothelial cells on the arterial wall damaged by various means were initially thought to be replaced by replication of neighboring cells. Smooth-muscle cells (SMCs) were also thought to migrate from the media into the intima, where they constituted arteriosclerotic lesions. This concept has been challenged,
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