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Cytokinetics and regulation of progenitor cells
Journal of Cellular Physiology, 1966Four different assay methods of bone marrow stem cells have been examined with regard to the kinetic pattern following perturbation of the steady-state system, e.g., by irradiation. Basically, the stem cell assays fall into two categories: those depending on grafting hemopoietic cells into suitably treated recipients, and those in which recovery of the
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B cells talk to their progenitors
Blood, 2011In this issue of Blood, Keren and colleagues report the existence of novel aging-associated cross-talk between the peripheral B-cell compartment and progenitors in the bone marrow, which negatively regulates B-cell production.1 This pathway could represent a target for therapeutic intervention in aged individuals who suffer from recurrent infection ...
John C. Cambier, Arnaud Van Den Broeck
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Adult Stem and Progenitor Cells
2009The discovery of adult stem cells in most adult tissues is the basis of a number of clinical studies that are carried out, with therapeutic use of hematopoietic stem cells as a prime example. Intense scientific debate is still ongoing as to whether adult stem cells may have a greater plasticity than previously thought. Although cells with some features
Catherine M. Verfaillie +1 more
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Progenitor cells in vascular repair
Current Opinion in Lipidology, 2007A common characteristic of all types of vascular disease is endothelial dysfunction/damage followed by an inflammatory response. Although mature endothelial cells can proliferate and replace damaged cells in the vessel wall, recent findings indicate an impact of stem and progenitor cells in repair process.
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Glia as neural progenitor cells
Trends in Neurosciences, 2003Recent studies have substantially expanded our conception of the roles for glia in function and maintenance of the adult nervous system. Of these reports, several have re-examined the lineage relationships among neural stem cells, their early radial glial derivatives and their mitotically competent neurogenic daughters.
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Hematopoietic Progenitor Cell Collection
2012Hematopoietic progenitor cells can be mobilized from the bone marrow microenvironment into the peripheral blood following treatment of patients with myeloid cytokines (GCSF, GMCSF, IL3), a CXCR4 antagonist (Plerixafor) and/or following a hematopoietic recovery from cytotoxic chemotherapy. The hematopoietic stem and progenitor cells are contained within
S. Darlene Marlow, Myra House
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, 2000 Immortalization of hepatic progenitor cells
Pathologie Biologie, 2004Development of cell therapy-based strategies for the treatment of liver failures and of inherited metabolic diseases has become a necessity because of the limitations of orthotopic liver transplantation, including shortage of donor livers. This shortage limits also the availability for hepatocytes and these terminally differentiated cells cannot be ...
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2016
Systemic sclerosis (SSc) is characterized by excessive fibrosis and microvasculopathy with deficiency in vascular formation and repair. The postnatal vascular system is constantly maintained through angiogenesis and vasculogenesis. Endothelial progenitor cells (EPCs), major players of vasculogenesis, are heterogeneous cell population containing an ...
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Systemic sclerosis (SSc) is characterized by excessive fibrosis and microvasculopathy with deficiency in vascular formation and repair. The postnatal vascular system is constantly maintained through angiogenesis and vasculogenesis. Endothelial progenitor cells (EPCs), major players of vasculogenesis, are heterogeneous cell population containing an ...
openaire +2 more sources